Abstract
Five adult female patients with Down's syndrome were compared with five age-matched controls in the standing and cold pressor tests. In both tests, there were no differences between the two groups in heart rate, systolic and diastolic blood pressure or plasma noradrenaline, adrenaline and dopamine concentrations. However, plasma adrenaline tended to be higher in the Down's group, both in the standing and the cold pressor tests.
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Selected References
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- Bühler H. U., da Prada M., Haefely W., Picotti G. B. Plasma adrenaline, noradrenaline and dopamine in man and different animal species. J Physiol. 1978 Mar;276:311–320. doi: 10.1113/jphysiol.1978.sp012235. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Coleman M., Campbell M., Freedman L. S., Roffman M., Ebstein R. P., Goldstein M. Serum dopamine-beta-hydroxylase levels in Down's syndrome. Clin Genet. 1974;5(4):312–315. doi: 10.1111/j.1399-0004.1974.tb01699.x. [DOI] [PubMed] [Google Scholar]
- Da Prada M., Zürcher Simultaneous radioenzymatic determination of plasma and tissue adrenaline, noradrenaline and dopamine within the femtomole range. Life Sci. 1976 Oct 15;19(8):1161–1174. doi: 10.1016/0024-3205(76)90251-4. [DOI] [PubMed] [Google Scholar]
- Freedman L. S., Goldstein M., Coleman M. Serum dopamine-beta-hydroxylase activity in Down's syndrome: a familial study. Res Commun Chem Pathol Pharmacol. 1974 Jul;8(3):543–549. [PubMed] [Google Scholar]
- Goldstein M., Freedman L. S., Ebstein R. P., Park D. H. Studies on dopamine-beta-hydroxylase in mental disorders. J Psychiatr Res. 1974;11:205–210. doi: 10.1016/0022-3956(74)90094-6. [DOI] [PubMed] [Google Scholar]
- Kopin I. J., Lake R. C., Ziegler M. Plasma levels of norepinephrine. Ann Intern Med. 1978 May;88(5):671–680. doi: 10.7326/0003-4819-88-5-671. [DOI] [PubMed] [Google Scholar]