Skip to main content
NCBI home page
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1985 Dec;48(12):1265–1268. doi: 10.1136/jnnp.48.12.1265

Laser injury of peripheral nerve: a model for focal endoneurial damage.

R R Myers, H E James, H C Powell
PMCID: PMC1028612  PMID: 4087002

Abstract

A model of endoneurial oedema is presented which produces localised nerve fibre injury including Wallerian degeneration, endoneurial oedema and increased endoneurial fluid pressure. A carbon dioxide laser was used to irradiate rat sciatic nerve and quantitative results were collected 2 days and 6 days after irradiation. The increase in endoneurial fluid pressure is compared with other models of Wallerian degeneration in which the entire fascicle was involved to aid in a comparative study of the role of oedema in neuropathy.

Full text

PDF
1265

Images in this article

1266Image
on p.1266
1266Image
on p.1266
1266Image
on p.1266

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Benson V. M., McLaurin R. L., Foulkes E. C. Traumatic cerebral edema. An experimental model with evaluation of dexamethasone. Arch Neurol. 1970 Aug;23(2):179–186. doi: 10.1001/archneur.1970.00480260085012. [DOI] [PubMed] [Google Scholar]
  2. Boggan J. E., Edwards M. S., Davis R. L., Bolger C. A., Martin N. Comparison of the brain tissue response in rats to injury by argon and carbon dioxide lasers. Neurosurgery. 1982 Nov;11(5):609–616. doi: 10.1227/00006123-198211000-00004. [DOI] [PubMed] [Google Scholar]
  3. Edwards M. S., Boggan J. E., Fuller T. A. The laser in neurological surgery. J Neurosurg. 1983 Oct;59(4):555–566. doi: 10.3171/jns.1983.59.4.0555. [DOI] [PubMed] [Google Scholar]
  4. Lombard G. F., Benech F., Tealdi S., Ponzio R. M. Thermal effects on nervous human tissues under electro or laser surgery. J Neurosurg Sci. 1982 Oct-Dec;26(4):265–271. [PubMed] [Google Scholar]
  5. Myers R. R., Heckman H. M., Powell H. C. Endoneurial fluid is hypertonic. Results of microanalysis and its significance in neuropathy. J Neuropathol Exp Neurol. 1983 May;42(3):217–224. doi: 10.1097/00005072-198305000-00001. [DOI] [PubMed] [Google Scholar]
  6. Myers R. R., Mizisin A. P., Powell H. C., Lampert P. W. Reduced nerve blood flow in hexachlorophene neuropathy: relationship to elevated endoneurial fluid pressure. J Neuropathol Exp Neurol. 1982 Jul;41(4):391–399. doi: 10.1097/00005072-198207000-00002. [DOI] [PubMed] [Google Scholar]
  7. Myers R. R., Powell H. C., Costello M. L., Lampert P. W., Zweifach B. W. Endoneurial fluid pressure: direct measurement with micropipettes. Brain Res. 1978 Jun 16;148(2):510–515. doi: 10.1016/0006-8993(78)90739-4. [DOI] [PubMed] [Google Scholar]
  8. Myers R. R., Powell H. C. Galactose neuropathy: impact of chronic endoneurial edema on nerve blood flow. Ann Neurol. 1984 Nov;16(5):587–594. doi: 10.1002/ana.410160510. [DOI] [PubMed] [Google Scholar]
  9. Myers R. R., Powell H. C., Heckman H. M., Costello M. L., Katz J. Biophysical and pathological effects of cryogenic nerve lesion. Ann Neurol. 1981 Nov;10(5):478–485. doi: 10.1002/ana.410100512. [DOI] [PubMed] [Google Scholar]
  10. Myers R. R., Powell H. C., Shapiro H. M., Costello M. L., Lampert P. W. Changes in endoneurial fluid pressure, permeability, and peripheral nerve ultrastructure in experimental lead neuropathy. Ann Neurol. 1980 Oct;8(4):392–401. doi: 10.1002/ana.410080410. [DOI] [PubMed] [Google Scholar]
  11. Powell H. C., Myers R. R., Costello M. L., Lampert P. W. Endoneurial fluid pressure in wallerian degeneration. Ann Neurol. 1979 Jun;5(6):550–557. doi: 10.1002/ana.410050610. [DOI] [PubMed] [Google Scholar]
  12. Powell H. C., Myers R. R. Schwann cell changes and demyelination in chronic galactose neuropathy. Muscle Nerve. 1983 Mar-Apr;6(3):218–227. doi: 10.1002/mus.880060309. [DOI] [PubMed] [Google Scholar]
  13. Ross M. H., Reith E. J. Perineurium: evidence for contractile elements. Science. 1969 Aug 8;165(3893):604–606. doi: 10.1126/science.165.3893.604. [DOI] [PubMed] [Google Scholar]
  14. Svaasand L. O., Ellingsen R. Optical properties of human brain. Photochem Photobiol. 1983 Sep;38(3):293–299. doi: 10.1111/j.1751-1097.1983.tb02674.x. [DOI] [PubMed] [Google Scholar]
  15. Toya S., Kawase T., Iisaka Y., Iwata T., Aki T., Nakamura T. Acute effect of the carbon dioxide laser on the epicerebral microcirculation. Experimental study by fluorescein angiography. J Neurosurg. 1980 Aug;53(2):193–197. doi: 10.3171/jns.1980.53.2.0193. [DOI] [PubMed] [Google Scholar]
  16. Weinreb R. N., Ruderman J., Juster R., Zweig K. Immediate intraocular pressure response to argon laser trabeculoplasty. Am J Ophthalmol. 1983 Mar;95(3):279–286. doi: 10.1016/s0002-9394(14)78294-7. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES