Abstract
Jaw, blink and corneal reflexes, which all involve the trigeminal system, were recorded in 54 patients with multiple sclerosis; thirty-seven of these patients were classified as having definite multiple sclerosis and 17 as indefinite multiple sclerosis, according to Schumacher's criteria. The jaw reflex was abnormal less frequently than either of the other two reflexes, but in four cases it was the only abnormal reflex found. Testing a combination of two or three trigeminal reflexes did not yield a higher incidence of abnormalities than testing the blink or corneal reflex alone. Nine patients showed abnormal reflexes which were unexpected on the basis of clinical symptoms. The combined recordings demonstrate at least one abnormal reflex in 74% of the patients. The various types of reflex abnormalities reflect major damage to different parts of the trigeminal system and may therefore make an important contribution to the diagnosis of multiple sclerosis.
Full text
PDF





Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Ferguson I. T. Electrical study of jaw and orbicularis oculi reflexes after trigeminal nerve surgery. J Neurol Neurosurg Psychiatry. 1978 Sep;41(9):819–823. doi: 10.1136/jnnp.41.9.819. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Goodwill C. J., O'Tuama L. Electromyographic recording of the jaw reflex in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1969 Feb;32(1):6–10. doi: 10.1136/jnnp.32.1.6. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KUGELBERG E. [Facial reflexes]. Brain. 1952 Sep;75(3):385–396. doi: 10.1093/brain/75.3.385. [DOI] [PubMed] [Google Scholar]
- Khoshbin S., Hallett M. Multimodality evoked potentials and blink reflex in multiple sclerosis. Neurology. 1981 Feb;31(2):138–144. doi: 10.1212/wnl.31.2.138. [DOI] [PubMed] [Google Scholar]
- Kimura J. Electrically elicited blink reflex in diagnosis of multiple sclerosis. Review of 260 patients over a seven-year period. Brain. 1975 Sep;98(3):413–426. doi: 10.1093/brain/98.3.413. [DOI] [PubMed] [Google Scholar]
- Kjaer M. The value of brain stem auditory, visual and somatosensory evoked potentials and blink reflexes in the diagnosis of multiple sclerosis. Acta Neurol Scand. 1980 Oct;62(4):220–236. doi: 10.1111/j.1600-0404.1980.tb03029.x. [DOI] [PubMed] [Google Scholar]
- Lacquaniti F., Benna P., Gilli M., Troni W., Bergamasco B. Brain stem auditory evoked potentials and blink reflexes in quiescent multiple sclerosis. Electroencephalogr Clin Neurophysiol. 1979 Nov;47(5):607–610. doi: 10.1016/0013-4694(79)90262-1. [DOI] [PubMed] [Google Scholar]
- Lowitzsch K., Kuhnt U., Sakmann C., Maurer K., Hopf H. C., Schott D., Thäter K. Visual pattern evoked responses and blink reflexes in assessment of MS diagnosis. A clinical study of 135 multiple sclerosis/pathol. J Neurol. 1976 Jul 15;213(1):17–32. doi: 10.1007/BF00316336. [DOI] [PubMed] [Google Scholar]
- Namerow N. S., Etemadi A. The orbicularis oculi reflex in multiple sclerosis. Neurology. 1970 Dec;20(12):1200–1203. doi: 10.1212/wnl.20.12.1200. [DOI] [PubMed] [Google Scholar]
- Ongerboer De Visser B. W., Goor C. Jaw reflexes and masseter electromyograms in mesencephalic and pontine lesions: an electrodiagnostic study. J Neurol Neurosurg Psychiatry. 1976 Jan;39(1):90–92. doi: 10.1136/jnnp.39.1.90. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ongerboer de Visser B. W. Afferent limb of the human jaw reflex: electrophysiologic and anatomic study. Neurology. 1982 May;32(5):563–566. doi: 10.1212/wnl.32.5.563. [DOI] [PubMed] [Google Scholar]
- Ongerboer de Visser B. W. Anatomical and functional organization of reflexes involving the trigeminal system in man: jaw reflex, blink reflex, corneal reflex, and exteroceptive suppression. Adv Neurol. 1983;39:727–738. [PubMed] [Google Scholar]
- Ongerboer de Visser B. W., Goor C. Electromyographic and reflex study in idiopathic and symptomatic trigeminal neuralgias: latency of the jaw and blink reflexes. J Neurol Neurosurg Psychiatry. 1974 Nov;37(11):1225–1230. doi: 10.1136/jnnp.37.11.1225. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ongerboer de Visser B. W., Kuypers H. G. Late blink reflex changes in lateral medullary lesions. An electrophysiological and neuro-anatomical study of Wallenberg's Syndrome. Brain. 1978 Jun;101(2):285–294. doi: 10.1093/brain/101.2.285. [DOI] [PubMed] [Google Scholar]
- Ongerboer de Visser B. W., Melchelse K., Megens P. H. Corneal reflex latency in trigeminal nerve lesions. Neurology. 1977 Dec;27(12):1164–1167. doi: 10.1212/wnl.27.12.1164. [DOI] [PubMed] [Google Scholar]
- Ongerboer de Visser B. W., Moffie D. Effects of brain-stem and thalamic lesions on the corneal reflex: an electrophysiological and anatomical study. Brain. 1979 Sep;102(3):595–608. doi: 10.1093/brain/102.3.595. [DOI] [PubMed] [Google Scholar]
- Tackmann W., Strenge H., Barth R., Sojka-Raytscheff A. Evaluation of various brain structures in multiple sclerosis with multimodality evoked potentials, blink reflex and nystagmography. J Neurol. 1980;224(1):33–46. doi: 10.1007/BF00313205. [DOI] [PubMed] [Google Scholar]
- Yates S. K., Brown W. F. Light-stimulus-evoked blink reflex: methods, normal values, relation to other blink reflexes, and observations in multiple sclerosis. Neurology. 1981 Mar;31(3):272–281. doi: 10.1212/wnl.31.3.272. [DOI] [PubMed] [Google Scholar]
- Yates S. K., Brown W. F. The human jaw jerk: electrophysiologic methods to measure the latency, normal values, and changes in multiple sclerosis. Neurology. 1981 May;31(5):632–634. doi: 10.1212/wnl.31.5.632. [DOI] [PubMed] [Google Scholar]