Abstract
Following chemotherapy with cis-diamminedichloroplatinum II (cisplatin) three patients developed Lhermitte's sign and peripheral neuropathy. The toxic side effects did not become apparent until after treatment had ceased. Because of increasing use of cisplatin to achieve lasting remission in patients with malignant disease proprioceptive and myelopathic side effects may become increasingly common.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Cowan J. D., Kies M. S., Roth J. L., Joyce R. P. Nerve conduction studies in patients treated with cis-diamminedichloroplatinum(II): a preliminary report. Cancer Treat Rep. 1980 Oct-Nov;64(10-11):1119–1122. [PubMed] [Google Scholar]
- Critchlow J. F., Seybold M. E., Jablecki C. J. The superficial radial nerve: techniques for evaluation. J Neurol Neurosurg Psychiatry. 1980 Oct;43(10):929–933. doi: 10.1136/jnnp.43.10.929. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GILLIATT R. W., SEARS T. A. Sensory nerve action potentials in patients with peripheral nerve lesions. J Neurol Neurosurg Psychiatry. 1958 May;21(2):109–118. doi: 10.1136/jnnp.21.2.109. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gautier-Smith P. C. Lhermitte's sign in subacute combined degeneration of the cord. J Neurol Neurosurg Psychiatry. 1973 Oct;36(5):861–863. doi: 10.1136/jnnp.36.5.861. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gershenson D. M., Wharton J. T., Herson J., Edwards C. L., Rutledge F. N. Single-agent cis-platinum therapy for advanced ovarian cancer. Obstet Gynecol. 1981 Oct;58(4):487–496. [PubMed] [Google Scholar]
- Guiloff R. J., Sherratt R. M. Sensory conduction in medial plantar nerve: normal values, clinical applications, and a comparison with the sural and upper limb sensory nerve action potentials in peripheral neuropathy. J Neurol Neurosurg Psychiatry. 1977 Dec;40(12):1168–1181. doi: 10.1136/jnnp.40.12.1168. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Horwich M. S., Cho L., Porro R. S., Posner J. B. Subacute sensory neuropathy: a remote effect of carcinoma. Ann Neurol. 1977 Jul;2(1):7–19. doi: 10.1002/ana.410020103. [DOI] [PubMed] [Google Scholar]
- JONES A. TRANSIENT RADIATION MYELOPATHY (WITH REFERENCE TO LHERMITTE'S SIGN OF ELECTRICAL PARAESTHESIA). Br J Radiol. 1964 Oct;37:727–744. doi: 10.1259/0007-1285-37-442-727. [DOI] [PubMed] [Google Scholar]
- Kaplan R. S., Wiernik P. H. Neurotoxicity of antineoplastic drugs. Semin Oncol. 1982 Mar;9(1):103–130. [PubMed] [Google Scholar]
- Lewis R. A., Sumner A. J. The electrodiagnostic distinctions between chronic familial and acquired demyelinative neuropathies. Neurology. 1982 Jun;32(6):592–596. doi: 10.1212/wnl.32.6.592. [DOI] [PubMed] [Google Scholar]
- Roelofs R. I., Hrushesky W., Rogin J., Rosenberg L. Peripheral sensory neuropathy and cisplatin chemotherapy. Neurology. 1984 Jul;34(7):934–938. doi: 10.1212/wnl.34.7.934. [DOI] [PubMed] [Google Scholar]
- Rosenfeld C. S., Broder L. E. Cisplatin-induced autonomic neuropathy. Cancer Treat Rep. 1984 Apr;68(4):659–660. [PubMed] [Google Scholar]
- Stålberg E., Chu J., Bril V., Nandedkar S., Stålberg S., Ericsson M. Automatic analysis of the EMG interference pattern. Electroencephalogr Clin Neurophysiol. 1983 Dec;56(6):672–681. doi: 10.1016/0013-4694(83)90035-4. [DOI] [PubMed] [Google Scholar]
- Thompson S. W., Davis L. E., Kornfeld M., Hilgers R. D., Standefer J. C. Cisplatin neuropathy. Clinical, electrophysiologic, morphologic, and toxicologic studies. Cancer. 1984 Oct 1;54(7):1269–1275. doi: 10.1002/1097-0142(19841001)54:7<1269::aid-cncr2820540707>3.0.co;2-9. [DOI] [PubMed] [Google Scholar]
- Walsh T. J., Clark A. W., Parhad I. M., Green W. R. Neurotoxic effects of cisplatin therapy. Arch Neurol. 1982 Nov;39(11):719–720. doi: 10.1001/archneur.1982.00510230045013. [DOI] [PubMed] [Google Scholar]