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. 1986 Mar;49(3):313–315. doi: 10.1136/jnnp.49.3.313

Brainstem reflexes and brainstem auditory evoked responses in Huntington's chorea.

E Bollen, R J Arts, R A Roos, E A van der Velde, O J Buruma
PMCID: PMC1028732  PMID: 2937885

Abstract

Blink reflex, corneal reflex, jaw reflex, exteroceptive suppression in masseter muscles and brainstem auditory evoked potentials were measured in 20 patients with Huntington's chorea and 12 controls. A significantly increased latency of the second component of the homolateral and heterolateral blink reflex was found in the patient group as compared with the controls. The other investigations revealed no significant differences between patients and controls except for some facilitation of the jaw reflex in the patient group. Increase of second component latency of the blink reflex in the presence of normal corneal reflexes is suggestive of functional impulse conduction disturbance in the lower brainstem. It is discussed whether in Huntington's chorea this is to be attributed to alterations of cortical or striatal influence or to local brainstem abnormalities.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Berardelli A., Accornero N., Cruccu G., Fabiano F., Guerrisi V., Manfredi M. The orbicularis oculi response after hemispheral damage. J Neurol Neurosurg Psychiatry. 1983 Sep;46(9):837–843. doi: 10.1136/jnnp.46.9.837. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Caraceni T., Avanzini G., Spreafico R., Negri S., Broggi G., Girotti F. Study of the excitability cycle of the blink reflex in Huntington's chorea. Eur Neurol. 1976;14(6):465–472. doi: 10.1159/000114774. [DOI] [PubMed] [Google Scholar]
  3. Ehle A. L., Stewart R. M., Lellelid N. A., Leventhal N. A. Evoked potentials in Huntington's disease. A comparative and longitudinal study. Arch Neurol. 1984 Apr;41(4):379–382. doi: 10.1001/archneur.1984.04050160041013. [DOI] [PubMed] [Google Scholar]
  4. Ferguson I. T., Lenman J. A., Johnston B. B. Habituation of the orbicularis oculi reflex in dementia and dyskinetic states. J Neurol Neurosurg Psychiatry. 1978 Sep;41(9):824–828. doi: 10.1136/jnnp.41.9.824. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Jewett D. L., Williston J. S. Auditory-evoked far fields averaged from the scalp of humans. Brain. 1971;94(4):681–696. doi: 10.1093/brain/94.4.681. [DOI] [PubMed] [Google Scholar]
  6. Leigh R. J., Newman S. A., Folstein S. E., Lasker A. G., Jensen B. A. Abnormal ocular motor control in Huntington's disease. Neurology. 1983 Oct;33(10):1268–1275. doi: 10.1212/wnl.33.10.1268. [DOI] [PubMed] [Google Scholar]
  7. Offner H., Fog T., Clausen J. Correlation between incorporation of myo-(2-3H)inositol into the phosphatidylinositol of lymphocytes and disability degree, stage and duration of multiple sclerosis. Acta Neurol Scand. 1975 Jul;52(1):1–6. [PubMed] [Google Scholar]
  8. Ongerboer De Visser B. W., Goor C. Jaw reflexes and masseter electromyograms in mesencephalic and pontine lesions: an electrodiagnostic study. J Neurol Neurosurg Psychiatry. 1976 Jan;39(1):90–92. doi: 10.1136/jnnp.39.1.90. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Ongerboer de Visser B. W. Anatomical and functional organization of reflexes involving the trigeminal system in man: jaw reflex, blink reflex, corneal reflex, and exteroceptive suppression. Adv Neurol. 1983;39:727–738. [PubMed] [Google Scholar]
  10. Ongerboer de Visser B. W., Goor C. Cutaneous silent period in masseter muscles: a clinical and electrodiagnostic evaluation. J Neurol Neurosurg Psychiatry. 1976 Jul;39(7):674–679. doi: 10.1136/jnnp.39.7.674. [DOI] [PMC free article] [PubMed] [Google Scholar]

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