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. 1986 Apr;49(4):411–418. doi: 10.1136/jnnp.49.4.411

Intracranial stimulation of the trigeminal nerve in man. I. Direct motor responses.

G Cruccu
PMCID: PMC1028768  PMID: 3701350

Abstract

Direct electrical stimulation of the intracranial portion of the trigeminal nerve was performed in 23 subjects undergoing retrogasserian thermocoagulation for the treatment of idiopathic trigeminal neuralgia. In 16 subjects, who were having the operation for the first time, neurological examination was normal, as was neurophysiological testing of trigeminal function. Seven subjects were being operated for the second time, owing to a recurrence of symptoms. In all the subjects being operated for the first time, direct motor responses were obtained from ipsilateral temporalis, masseter and anterior belly of the digastric. The motor conduction velocity was equal for the fibres directed to all three muscles. This was estimated to be 54m/s in the masseteric nerve and 55-68 m/s in the intracranial portion of the trigeminal nerve. Patients who had undergone previous thermocoagulation had a considerably slower conduction velocity. It is supposed that myelin sheaths had been damaged at the first operation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BEAVER D. L., MOSES H. L., GANOTE C. E. ELECTRON MICROSCOPY OF THE TRIGEMINAL GANGLION. 3. TRIGEMINAL NEURALGIA. Arch Pathol. 1965 Jun;79:571–582. [PubMed] [Google Scholar]
  2. Cruccu G., Agostino R., Fornarelli M., Inghilleri M., Manfredi M. Recovery cycle of the masseter inhibitory reflex in man. Neurosci Lett. 1984 Aug 24;49(1-2):63–68. doi: 10.1016/0304-3940(84)90137-x. [DOI] [PubMed] [Google Scholar]
  3. Cruccu G., Bowsher D. Intracranial stimulation of the trigeminal nerve in man. II. Reflex responses. J Neurol Neurosurg Psychiatry. 1986 Apr;49(4):419–427. doi: 10.1136/jnnp.49.4.419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Cruccu G., Fornarelli M., Inghilleri M., Manfredi M. Reflex and cortical responses to dental stimuli. Ital J Neurol Sci. 1983 Sep;4(3):309–315. doi: 10.1007/BF02043484. [DOI] [PubMed] [Google Scholar]
  5. Ferguson I. T. Electrical study of jaw and orbicularis oculi reflexes after trigeminal nerve surgery. J Neurol Neurosurg Psychiatry. 1978 Sep;41(9):819–823. doi: 10.1136/jnnp.41.9.819. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Fujii H. Electromyographic F and H--F-complex responses of jaw closing muscles in man. Arch Oral Biol. 1979;24(10-11):843–845. doi: 10.1016/0003-9969(79)90048-7. [DOI] [PubMed] [Google Scholar]
  7. Geraldini C., Faedda M. T., Sideri G. Anticonvulsant therapy and its possible consequences on peripheral nervous system: a neurographic study. Epilepsia. 1984 Aug;25(4):502–505. doi: 10.1111/j.1528-1157.1984.tb03451.x. [DOI] [PubMed] [Google Scholar]
  8. Godaux E., Desmedt J. E. Human masseter muscle: H- and tendon reflexes. Their paradoxical potentiation by muscle vibration. Arch Neurol. 1975 Apr;32(4):229–234. doi: 10.1001/archneur.1975.00490460045005. [DOI] [PubMed] [Google Scholar]
  9. Goodwill C. J. The normal jaw reflex: measurement of the action potential in the masseter muscles. Ann Phys Med. 1968 Feb;9(5):183–188. doi: 10.1093/rheumatology/9.5.183. [DOI] [PubMed] [Google Scholar]
  10. Gudmundsson K., Rhoton A. L., Jr, Rushton J. G. Detailed anatomy of the intracranial portion of the trigeminal nerve. J Neurosurg. 1971 Nov;35(5):592–600. doi: 10.3171/jns.1971.35.5.0592. [DOI] [PubMed] [Google Scholar]
  11. Henderson W. R. Trigeminal neuralgia: the pain and its treatment. Br Med J. 1967 Jan 7;1(5531):7–15. doi: 10.1136/bmj.1.5531.7. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. KUGELBERG E. [Facial reflexes]. Brain. 1952 Sep;75(3):385–396. doi: 10.1093/brain/75.3.385. [DOI] [PubMed] [Google Scholar]
  13. Kerr F. W. Evidence for a peripheral etiology of trigeminal neuralgia. J Neurosurg. 1967 Jan;26(1 Suppl):168–174. doi: 10.3171/jns.1967.26.1part2.0168. [DOI] [PubMed] [Google Scholar]
  14. Kerr F. W., Miller R. H. The pathology of trigeminal neuralgia. Electron microscopic studies. Arch Neurol. 1966 Sep;15(3):308–319. doi: 10.1001/archneur.1966.00470150086014. [DOI] [PubMed] [Google Scholar]
  15. Kimura J. Clinical uses of the electrically elicited blink reflex. Adv Neurol. 1983;39:773–786. [PubMed] [Google Scholar]
  16. Kimura J. F-wave determination in nerve conduction studies. Adv Neurol. 1983;39:961–975. [PubMed] [Google Scholar]
  17. Kimura J., Rodnitzky R. L., Van Allen M. W. Electrodiagnostic study of trigeminal nerve. Orbicularis oculi reflex and masseter reflex in trigeminal neuralgia, paratrigeminal syndrome, and other lesions of the trigeminal nerve. Neurology. 1970 Jun;20(6):574–583. doi: 10.1212/wnl.20.6.574. [DOI] [PubMed] [Google Scholar]
  18. Lahuerta J., Lipton S., Miles J. Percutaneous radio frequency gangliolysis in the treatment of trigeminal neuralgia. Eur Neurol. 1985;24(4):272–275. doi: 10.1159/000115806. [DOI] [PubMed] [Google Scholar]
  19. Leandri M., Parodi C. I., Favale E. Early evoked potentials detected from the scalp of man following infraorbital nerve stimulation. Electroencephalogr Clin Neurophysiol. 1985 Mar;62(2):99–107. doi: 10.1016/0168-5597(85)90021-8. [DOI] [PubMed] [Google Scholar]
  20. MAGLADERY J. W., McDOUGAL D. B., Jr Electrophysiological studies of nerve and reflex activity in normal man. I. Identification of certain reflexes in the electromyogram and the conduction velocity of peripheral nerve fibers. Bull Johns Hopkins Hosp. 1950 May;86(5):265–290. [PubMed] [Google Scholar]
  21. Ongerboer de Visser B. W., Goor C. Electromyographic and reflex study in idiopathic and symptomatic trigeminal neuralgias: latency of the jaw and blink reflexes. J Neurol Neurosurg Psychiatry. 1974 Nov;37(11):1225–1230. doi: 10.1136/jnnp.37.11.1225. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Rakhawy M. T., Shehata S. H., Badawy Z. H. The points of nerve entry and the intramuscular nerve branchings in the human muscles of mastication. Acta Anat (Basel) 1976;94(4):609–616. doi: 10.1159/000144592. [DOI] [PubMed] [Google Scholar]
  23. SKORPIL V., ZVERINA E. RYCHLOST VEDEN'I MOZKOV'YMI NERVY U CLOV EKA. Cesk Neurol. 1963 May;26:152–156. [PubMed] [Google Scholar]
  24. Saunders R. L., Krout R., Sachs E., Jr Masticator electromyography in trigeminal neuralgia. Neurology. 1971 Dec;21(12):1221–1225. doi: 10.1212/wnl.21.12.1221. [DOI] [PubMed] [Google Scholar]
  25. Stevens J. C., Lofgren E. P., Dyck P. J. Histometric evaluation of branches of peroneal nerve: technique for combined biopsy of muscle nerve and cutaneous nerve. Brain Res. 1973 Mar 30;52:37–59. doi: 10.1016/0006-8993(73)90649-5. [DOI] [PubMed] [Google Scholar]
  26. Sweet W. H., Wepsic J. G. Controlled thermocoagulation of trigeminal ganglion and rootlets for differential destruction of pain fibers. 1. Trigeminal neuralgia. J Neurosurg. 1974 Feb;40(2):143–156. doi: 10.3171/jns.1974.40.2.0143. [DOI] [PubMed] [Google Scholar]
  27. Trontelj M. A., Trontelj J. V. Reflex arc of the first component of the human blink reflex: a single motoneurone study. J Neurol Neurosurg Psychiatry. 1978 Jun;41(6):538–547. doi: 10.1136/jnnp.41.6.538. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Young R. F., Stevens R. Unmyelinated axons in the trigeminal motor root of human and cat. J Comp Neurol. 1979 Jan 1;183(1):205–214. doi: 10.1002/cne.901830114. [DOI] [PubMed] [Google Scholar]

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