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. 1986 Sep;49(9):1079–1083. doi: 10.1136/jnnp.49.9.1079

Aleukaemic leukostasis in a case of large cell non-Hodgkin's lymphoma: report of a case with a distinctive central nervous system involvement.

S Jain, D Kotasek, P C Blumbergs, R E Sage
PMCID: PMC1029019  PMID: 3760899

Abstract

A 52-year-old man with large cell non-Hodgkin's lymphoma developed a unique pattern of central nervous system involvement by lymphoma while in apparent systemic remission. Despite intermittent neurological episodes suggestive of CNS involvement by lymphoma no evidence of CNS lymphoma was found on repeated cerebrospinal fluid and brain CT scan examinations. At necropsy widespread occlusion of cerebral blood vessels by malignant lymphoid cells was observed with extensive tissue necrosis and haemorrhages. Leukaemic involvement of peripheral blood was not detected on repeated blood film examinations during life.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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