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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1986 Nov;49(11):1258–1265. doi: 10.1136/jnnp.49.11.1258

Is there a specific visuo-spatial impairment in Parkinsonians?

S Della Sala, G Di Lorenzo, A Giordano, H Spinnler
PMCID: PMC1029074  PMID: 3794731

Abstract

Twenty-five non-demented patients with mild, idiopathic, Parkinson's disease were compared with 25 age and education matched normal controls on a visuo-spatial performance task, whose characteristics were directional forecast, with minimal motor requirement and a maximal spatial load. No statistical support was found for the existence of spatial impairment in these patients.

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Selected References

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  1. Asso D. W.A.I.S. scores in a group of Parkinson patients. Br J Psychiatry. 1969 May;115(522):555–556. doi: 10.1192/bjp.115.522.555. [DOI] [PubMed] [Google Scholar]
  2. Bentin S., Silverberg R., Gordon H. W. Asymmetrical cognitive deterioration in demented and Parkinson patients. Cortex. 1981 Dec;17(4):533–543. doi: 10.1016/s0010-9452(81)80060-3. [DOI] [PubMed] [Google Scholar]
  3. Bodis-Wollner I., Yahr M. D. Measurements of visual evoked potentials in Parkinson's disease. Brain. 1978 Dec;101(4):661–671. doi: 10.1093/brain/101.4.661. [DOI] [PubMed] [Google Scholar]
  4. Bodis-Wollner I., Yahr M. D., Mylin L. H. Nonmotor functions of the basal ganglia. Adv Neurol. 1984;40:289–298. [PubMed] [Google Scholar]
  5. Boller F., Passafiume D., Keefe N. C., Rogers K., Morrow L., Kim Y. Visuospatial impairment in Parkinson's disease. Role of perceptual and motor factors. Arch Neurol. 1984 May;41(5):485–490. doi: 10.1001/archneur.1984.04050170031011. [DOI] [PubMed] [Google Scholar]
  6. Botez M. I., Barbeau A. Neuropsychological findings in Parkinson's disease: a comparison between various tests during long-term levodopa therapy. Int J Neurol. 1975;10(1-4):222–232. [PubMed] [Google Scholar]
  7. Bowen F. P. Behavioral alterations in patients with basal ganglia lesions. Res Publ Assoc Res Nerv Ment Dis. 1976;55:169–180. [PubMed] [Google Scholar]
  8. Bowen F. P., Burns M. M., Brady E. M., Yahr M. D. A note of alterations of personal orientation in Parkinsonism. Neuropsychologia. 1976;14(4):425–429. doi: 10.1016/0028-3932(76)90071-3. [DOI] [PubMed] [Google Scholar]
  9. Bowen F. P., Hoehn M. M., Yahr M. D. Parkinsonism: alterations in spatial orientation as determined by a route-walking test. Neuropsychologia. 1972 Sep;10(3):355–361. doi: 10.1016/0028-3932(72)90027-9. [DOI] [PubMed] [Google Scholar]
  10. Buschke H., Fuld P. A. Evaluating storage, retention, and retrieval in disordered memory and learning. Neurology. 1974 Nov;24(11):1019–1025. doi: 10.1212/wnl.24.11.1019. [DOI] [PubMed] [Google Scholar]
  11. CHOROVER S. L., GROSS C. G. CAUDATE NUCLEUS LESIONS: BEHAVIORAL EFFECTS IN THE RAT. Science. 1963 Aug 30;141(3583):826–827. doi: 10.1126/science.141.3583.826. [DOI] [PubMed] [Google Scholar]
  12. Danta G., Hilton R. C. Judgment of the visual vertical and horizontal in patients with Parkinsonism. Neurology. 1975 Jan;25(1):43–47. doi: 10.1212/wnl.25.1.43. [DOI] [PubMed] [Google Scholar]
  13. De Lancy Horne D. J. Performance on delayed response tasks by patients with parkinsonism. J Neurol Neurosurg Psychiatry. 1971 Apr;34(2):192–194. doi: 10.1136/jnnp.34.2.192. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. De Lancy Horne D. J. Performance on delayed response tasks by patients with parkinsonism. J Neurol Neurosurg Psychiatry. 1971 Apr;34(2):192–194. doi: 10.1136/jnnp.34.2.192. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Della Sala S., Nichelli P., Spinnler H. An Italian series of patients with organic dementia. Ital J Neurol Sci. 1986 Feb;7(1):27–41. doi: 10.1007/BF02230415. [DOI] [PubMed] [Google Scholar]
  16. Della Sala S., Spinnler H. 'Indifférence amnésique' in a case of global amnesia following acute brain hypoxia. Eur Neurol. 1986;25(2):98–109. doi: 10.1159/000115994. [DOI] [PubMed] [Google Scholar]
  17. Direnfeld L. K., Albert M. L., Volicer L., Langlais P. J., Marquis J., Kaplan E. Parkinson's disease. The possible relationship of laterality to dementia and neurochemical findings. Arch Neurol. 1984 Sep;41(9):935–941. doi: 10.1001/archneur.1984.04050200041016. [DOI] [PubMed] [Google Scholar]
  18. Fedio P., Van Buren J. M. Memory and perceptual deficits during electrical stimulation in the left and right thalamus and parietal subcortex. Brain Lang. 1975 Jan;2(1):78–100. doi: 10.1016/s0093-934x(75)80056-3. [DOI] [PubMed] [Google Scholar]
  19. Flowers K. Lack of prediction in the motor behaviour of Parkinsonism. Brain. 1978 Mar;101(1):35–52. doi: 10.1093/brain/101.1.35. [DOI] [PubMed] [Google Scholar]
  20. Flowers K. Some frequency response characteristics of Parkinsonism on pursuit tracking. Brain. 1978 Mar;101(1):19–34. doi: 10.1093/brain/101.1.19. [DOI] [PubMed] [Google Scholar]
  21. Gregory R. L. On how little information controls so much behaviour. Ergonomics. 1970 Jan;13(1):25–35. doi: 10.1080/00140137008931116. [DOI] [PubMed] [Google Scholar]
  22. Hoehn M. M., Yahr M. D. Parkinsonism: onset, progression and mortality. Neurology. 1967 May;17(5):427–442. doi: 10.1212/wnl.17.5.427. [DOI] [PubMed] [Google Scholar]
  23. LEVITA E., RIKLAN M., COOPER I. S. COGNITIVE AND PERCEPTUAL PERFORMANCE IN PARKINSONISM AS A FUNCTION OF AGE AND NEUROLOGICAL IMPAIRMENT. J Nerv Ment Dis. 1964 Dec;139:516–520. doi: 10.1097/00005053-196412000-00003. [DOI] [PubMed] [Google Scholar]
  24. Lees A. J., Smith E. Cognitive deficits in the early stages of Parkinson's disease. Brain. 1983 Jun;106(Pt 2):257–270. doi: 10.1093/brain/106.2.257. [DOI] [PubMed] [Google Scholar]
  25. Levita E., Riklan M. Integrative functions in parkinsonism. Percept Mot Skills. 1970 Oct;31(2):379–385. doi: 10.2466/pms.1970.31.2.379. [DOI] [PubMed] [Google Scholar]
  26. Lieberman A., Dziatolowski M., Kupersmith M., Serby M., Goodgold A., Korein J., Goldstein M. Dementia in Parkinson Disease. Ann Neurol. 1979 Oct;6(4):355–359. doi: 10.1002/ana.410060409. [DOI] [PubMed] [Google Scholar]
  27. Loranger A. W., Goodell H., McDowell F. H., Lee J. E., Sweet R. D. Intellectual impairment in Parkinson's syndrome. Brain. 1972;95(2):405–412. doi: 10.1093/brain/95.2.405. [DOI] [PubMed] [Google Scholar]
  28. Martin W. E., Loewenson R. B., Resch J. A., Baker A. B. Parkinson's disease. Clinical analysis of 100 patients. Neurology. 1973 Aug;23(8):783–790. doi: 10.1212/wnl.23.8.783. [DOI] [PubMed] [Google Scholar]
  29. Marttila R. J., Rinne U. K. Dementia in Parkinson's disease. Acta Neurol Scand. 1976 Nov;54(5):431–441. doi: 10.1111/j.1600-0404.1976.tb04375.x. [DOI] [PubMed] [Google Scholar]
  30. Matthews C. G., Haaland K. Y. The effect of symptom duration on cognitive and motor performance in parkinsonism. Neurology. 1979 Jul;29(7):951–956. doi: 10.1212/wnl.29.7.951. [DOI] [PubMed] [Google Scholar]
  31. Meier M. J., Martin W. E. Intellectual changes associated with levodopa therapy. JAMA. 1970 Jul 20;213(3):465–466. [PubMed] [Google Scholar]
  32. Mindham R. H., Ahmed S. W., Clough C. G. A controlled study of dementia in Parkinson's disease. J Neurol Neurosurg Psychiatry. 1982 Nov;45(11):969–974. doi: 10.1136/jnnp.45.11.969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Mortimer J. A., Pirozzolo F. J., Hansch E. C., Webster D. D. Relationship of motor symptoms to intellectual deficits in Parkinson disease. Neurology. 1982 Feb;32(2):133–137. doi: 10.1212/wnl.32.2.133. [DOI] [PubMed] [Google Scholar]
  34. Oldfield R. C. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 1971 Mar;9(1):97–113. doi: 10.1016/0028-3932(71)90067-4. [DOI] [PubMed] [Google Scholar]
  35. PROCTOR F., RIKLAN M., COOPER I. S., TEUBER H. L. JUDGMENT OF VISUAL AND POSTURAL VERTICAL BY PARKINSONIAN PATIENTS. Neurology. 1964 Apr;14:287–293. doi: 10.1212/wnl.14.4.287. [DOI] [PubMed] [Google Scholar]
  36. Pirozzolo F. J., Hansch E. C., Mortimer J. A., Webster D. D., Kuskowski M. A. Dementia in Parkinson disease: a neuropsychological analysis. Brain Cogn. 1982 Jan;1(1):71–83. doi: 10.1016/0278-2626(82)90007-0. [DOI] [PubMed] [Google Scholar]
  37. Pollock M., Hornabrook R. W. The prevalence, natural history and dementia of Parkinson's disease. Brain. 1966 Sep;89(3):429–448. doi: 10.1093/brain/89.3.429. [DOI] [PubMed] [Google Scholar]
  38. Potegal M. Role of the caudate nucleus in spatial orientation of rats. J Comp Physiol Psychol. 1969 Dec;69(4):756–764. doi: 10.1037/h0028168. [DOI] [PubMed] [Google Scholar]
  39. Rafal R. D., Posner M. I., Walker J. A., Friedrich F. J. Cognition and the basal ganglia. Separating mental and motor components of performance in Parkinson's disease. Brain. 1984 Dec;107(Pt 4):1083–1094. doi: 10.1093/brain/107.4.1083. [DOI] [PubMed] [Google Scholar]
  40. Reitan R. M., Boll T. J. Intellectual and cognitive functions in Parkinson's disease. J Consult Clin Psychol. 1971 Dec;37(3):364–369. doi: 10.1037/h0032005. [DOI] [PubMed] [Google Scholar]
  41. Rosvold H. E. The frontal lobe system: cortical-subcortical interrelationships. Acta Neurobiol Exp (Wars) 1972;32(2):439–460. [PubMed] [Google Scholar]
  42. Sadeh M., Braham J., Modan M. Effects of anticholinergic drugs on memory in Parkinson's disease. Arch Neurol. 1982 Oct;39(10):666–667. doi: 10.1001/archneur.1982.00510220064017. [DOI] [PubMed] [Google Scholar]
  43. Sitaram N., Weingartner H., Gillin J. C. Human serial learning: enhancement with arecholine and choline impairment with scopolamine. Science. 1978 Jul 21;201(4352):274–276. doi: 10.1126/science.351808. [DOI] [PubMed] [Google Scholar]
  44. Stern Y., Mayeux R., Côté L. Reaction time and vigilance in Parkinson's disease. Possible role of altered norepinephrine metabolism. Arch Neurol. 1984 Oct;41(10):1086–1089. doi: 10.1001/archneur.1984.04050210084021. [DOI] [PubMed] [Google Scholar]
  45. Stern Y., Mayeux R., Rosen J., Ilson J. Perceptual motor dysfunction in Parkinson's disease: a deficit in sequential and predictive voluntary movement. J Neurol Neurosurg Psychiatry. 1983 Feb;46(2):145–151. doi: 10.1136/jnnp.46.2.145. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Villardita C., Smirni P., le Pira F., Zappala G., Nicoletti F. Mental deterioration, visuoperceptive disabilities and constructional apraxia in Parkinson's disease. Acta Neurol Scand. 1982 Jul;66(1):112–120. doi: 10.1111/j.1600-0404.1982.tb03135.x. [DOI] [PubMed] [Google Scholar]

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