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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1986 Dec;49(12):1449–1451. doi: 10.1136/jnnp.49.12.1449

Phaeochromocytoma as a cause of reversible dementia.

P D White, W A Lishman, M A Wyke
PMCID: PMC1029135  PMID: 3806123

Abstract

The case of a 57 year old man with cognitive impairment, hypertension and insulin dependent diabetes mellitus caused by phaeochromocytoma is reported. One year after removal of the tumour there was a significant improvement with the full scale IQ increasing by 15 points, normotension and minimal glucose intolerance. Possible mechanisms accounting for reversible cognitive impairment in such a situation are discussed. No previous reports of this association have been discovered.

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Selected References

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  1. Caine E. D., Hunt R. D., Weingartner H., Ebert M. H. Huntington's dementia. Clinical and neuropsychological features. Arch Gen Psychiatry. 1978 Mar;35(3):377–384. doi: 10.1001/archpsyc.1978.01770270127013. [DOI] [PubMed] [Google Scholar]
  2. Fry J. Deaths and complications from hypertension. J R Coll Gen Pract. 1975 Jul;25(156):489–494. [PMC free article] [PubMed] [Google Scholar]
  3. Hachinski V. C., Lassen N. A., Marshall J. Multi-infarct dementia. A cause of mental deterioration in the elderly. Lancet. 1974 Jul 27;2(7874):207–210. doi: 10.1016/s0140-6736(74)91496-2. [DOI] [PubMed] [Google Scholar]
  4. Healton E. B., Brust J. C., Feinfeld D. A., Thomson G. E. Hypertensive encephalopathy and the neurologic manifestations of malignant hypertension. Neurology. 1982 Feb;32(2):127–132. doi: 10.1212/wnl.32.2.127. [DOI] [PubMed] [Google Scholar]
  5. Janota I. Dementia, deep white matter damage and hypertension: 'Binswanger's disease'. Psychol Med. 1981 Feb;11(1):39–48. doi: 10.1017/s0033291700053265. [DOI] [PubMed] [Google Scholar]
  6. McFie J., Thompson J. A. Picture arrangement: a measure of frontal lobe function? Br J Psychiatry. 1972 Nov;121(564):547–552. doi: 10.1192/bjp.121.5.547. [DOI] [PubMed] [Google Scholar]
  7. Schultz N. R., Jr, Dineen J. T., Elias M. F., Pentz C. A., 3rd, Wood W. G. WAIS performance for different age groups of hypertensive and control subjects during the administration of a diuretic. J Gerontol. 1979 Mar;34(2):246–253. doi: 10.1093/geronj/34.2.246. [DOI] [PubMed] [Google Scholar]
  8. Small G. W., Jarvik L. F. The dementia syndrome. Lancet. 1982 Dec 25;2(8313):1443–1446. doi: 10.1016/s0140-6736(82)91339-3. [DOI] [PubMed] [Google Scholar]
  9. Valentine A. R., Moseley I. F., Kendall B. E. White matter abnormality in cerebral atrophy: clinicoradiological correlations. J Neurol Neurosurg Psychiatry. 1980 Feb;43(2):139–142. doi: 10.1136/jnnp.43.2.139. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Wilkie F., Eisdorfer C. Intelligence and blood pressure in the aged. Science. 1971 May 28;172(3986):959–962. doi: 10.1126/science.172.3986.959. [DOI] [PubMed] [Google Scholar]

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