Abstract
The first description of an association of isolated growth hormone deficiency (IGHD) and combined immunodeficiency is presented. The findings suggest that IGHD should be considered as a cause of short stature in children with combined immunodeficiency before attributing growth retardation to infection.
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Selected References
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- Brooks E. G., Schmalstieg F. C., Wirt D. P., Rosenblatt H. M., Adkins L. T., Lookingbill D. P., Rudloff H. E., Rakusan T. A., Goldman A. S. A novel X-linked combined immunodeficiency disease. J Clin Invest. 1990 Nov;86(5):1623–1631. doi: 10.1172/JCI114884. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Conley M. E., Burks A. W., Herrod H. G., Puck J. M. Molecular analysis of X-linked agammaglobulinemia with growth hormone deficiency. J Pediatr. 1991 Sep;119(3):392–397. doi: 10.1016/s0022-3476(05)82051-7. [DOI] [PubMed] [Google Scholar]
- Fabris N., Pierpaoli W., Sorkin E. Hormones and the immunological capacity. IV. Restorative effects of developmental hormones or of lymphocytes on the immunodeficiency syndrome of the dwarf mouse. Clin Exp Immunol. 1971 Aug;9(2):227–240. [PMC free article] [PubMed] [Google Scholar]
- Fleisher T. A., White R. M., Broder S., Nissley S. P., Blaese R. M., Mulvihill J. J., Olive G., Waldmann T. A. X-linked hypogammaglobulinemia and isolated growth hormone deficiency. N Engl J Med. 1980 Jun 26;302(26):1429–1434. doi: 10.1056/NEJM198006263022601. [DOI] [PubMed] [Google Scholar]
- Griscelli C., Durandy A., Virelizier J. L., Ballet J. J., Daguillard F. Selective defect of precursor T cells associated with apparently normal B lymphocytes in severe combined immunodeficiency disease. J Pediatr. 1978 Sep;93(3):404–411. doi: 10.1016/s0022-3476(78)81146-9. [DOI] [PubMed] [Google Scholar]
- Lawlor G. J., Jr, Ammann A. J., Wright W. C., Jr, La Franchi S. H., Bilstrom D., Stiehm E. R. The syndrome of cellular immunodeficiency with immunoglobulins. J Pediatr. 1974 Feb;84(2):183–192. doi: 10.1016/s0022-3476(74)80599-8. [DOI] [PubMed] [Google Scholar]
- Monafo V., Maghnie M., Terracciano L., Valtorta A., Massa M., Severi F. X-linked agammaglobulinemia and isolated growth hormone deficiency. Acta Paediatr Scand. 1991 May;80(5):563–566. doi: 10.1111/j.1651-2227.1991.tb11907.x. [DOI] [PubMed] [Google Scholar]
- de Saint-Basile G., Le Deist F., Caniglia M., Lebranchu Y., Griscelli C., Fischer A. Genetic study of a new X-linked recessive immunodeficiency syndrome. J Clin Invest. 1992 Mar;89(3):861–866. doi: 10.1172/JCI115665. [DOI] [PMC free article] [PubMed] [Google Scholar]