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. 1993 Jun;68(6):779–782. doi: 10.1136/adc.68.6.779

Neurological and adrenal dysfunction in the adrenal insufficiency/alacrima/achalasia (3A) syndrome.

D B Grant 1, N D Barnes 1, M Dumic 1, M Ginalska-Malinowska 1, P J Milla 1, W von Petrykowski 1, R J Rowlatt 1, R Steendijk 1, J H Wales 1, E Werder 1
PMCID: PMC1029374  PMID: 8333772

Abstract

Review of 20 patients with glucocorticoid deficiency (three cases also with salt loss) associated with absent tear secretion (19 cases) and achalasia of the cardia (15 cases) revealed neurological abnormalities in 17 including hyper-reflexia, muscle weakness, dysarthria, and ataxia together with impaired intelligence and abnormal autonomic function, particularly postural hypotension. These findings indicate that significant neurological problems are common in this multisystem disorder.

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Selected References

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