Abstract
Against the background of reported different trends of incidence and presentation of coeliac disease in Sweden and Finland, a joint study was done to explore potential causes. The clinical study confirmed that classical symptoms and diagnosis before 2 years of age dominated in Sweden. In Finland, the symptoms were more diffuse and diagnosis in most cases was made after the age of 8 years. A significantly lower weight score attained at diagnosis was seen in Swedish patients compared with Finnish. No significant difference in HLA expression was found. Infant feeding was investigated by studying food records of healthy infants. Swedish infants ingested three times more wheat protein at 9 months and twice as much at 12 months compared with Finnish children. It is concluded that the intake of infant cereal protein might influence when and how clinical coeliac disease appears. The question whether or not it is important for if coeliac disease will be acquired still remains to be answered.
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- Ascher H., Krantz I., Kristiansson B. Increasing incidence of coeliac disease in Sweden. Arch Dis Child. 1991 May;66(5):608–611. doi: 10.1136/adc.66.5.608. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Berg N. O., Lindberg T. Incidence of coeliac disease and transient gluten intolerance in children in a Swedish urban community. Acta Paediatr Scand. 1979 May;68(3):397–400. doi: 10.1111/j.1651-2227.1979.tb05026.x. [DOI] [PubMed] [Google Scholar]
- Cavell B., Stenhammar L., Ascher H., Danielsson L., Dannaeus A., Lindberg T., Lindquist B. Increasing incidence of childhood coeliac disease in Sweden. Results of a national study. Acta Paediatr. 1992 Aug;81(8):589–592. doi: 10.1111/j.1651-2227.1992.tb12306.x. [DOI] [PubMed] [Google Scholar]
- Childhood coeliac disease is disappearing. Lancet. 1980 Dec 20;2(8208-8209):1359–1360. [PubMed] [Google Scholar]
- Collin P., Hällström O., Mäki M., Viander M., Keyriläinen O. Atypical coeliac disease found with serologic screening. Scand J Gastroenterol. 1990 Mar;25(3):245–250. [PubMed] [Google Scholar]
- Dossetor J. F., Gibson A. A., McNeish A. S. Childhood coeliac disease is disappearing. Lancet. 1981 Feb 7;1(8215):322–323. doi: 10.1016/s0140-6736(81)91926-7. [DOI] [PubMed] [Google Scholar]
- Greco L., Tozzi A. E., Mayer M., Grimaldi M., Silano G., Auricchio S. Unchanging clinical picture of coeliac disease presentation in Campania, Italy. Eur J Pediatr. 1989 Jun;148(7):610–613. doi: 10.1007/BF00441511. [DOI] [PubMed] [Google Scholar]
- Grodzinsky E., Franzen L., Hed J., Ström M. High prevalence of celiac disease in healthy adults revealed by antigliadin antibodies. Ann Allergy. 1992 Jul;69(1):66–70. [PubMed] [Google Scholar]
- Karlberg J. On the construction of the infancy-childhood-puberty growth standard. Acta Paediatr Scand Suppl. 1989;356:26–37. doi: 10.1111/j.1651-2227.1989.tb11237.x. [DOI] [PubMed] [Google Scholar]
- Karlberg P., Taranger J. The somatic development of children in a swedish urban community. Acta Paediatr Scand Suppl. 1976;(258):1–148. [PubMed] [Google Scholar]
- Kristiansson B. Tillväxtkurvan vid diagnostik och behandling av barn i förskoleåldern. Nord Med. 1987;102(10):272–275. [PubMed] [Google Scholar]
- Lindberg T. Coeliac disease and infant feeding practices. Lancet. 1981 Feb 21;1(8217):449–449. doi: 10.1016/s0140-6736(81)91837-7. [DOI] [PubMed] [Google Scholar]
- Logan R. F., Rifkind E. A., Busuttil A., Gilmour H. M., Ferguson A. Prevalence and "incidence" of celiac disease in Edinburgh and the Lothian region of Scotland. Gastroenterology. 1986 Feb;90(2):334–342. doi: 10.1016/0016-5085(86)90929-7. [DOI] [PubMed] [Google Scholar]
- Mäki M., Holm K. Incidence and prevalence of coeliac disease in Tampere. Coeliac disease is not disappearing. Acta Paediatr Scand. 1990 Oct;79(10):980–982. doi: 10.1111/j.1651-2227.1990.tb11367.x. [DOI] [PubMed] [Google Scholar]
- Mäki M., Kallonen K., Lähdeaho M. L., Visakorpi J. K. Changing pattern of childhood coeliac disease in Finland. Acta Paediatr Scand. 1988 May;77(3):408–412. doi: 10.1111/j.1651-2227.1988.tb10668.x. [DOI] [PubMed] [Google Scholar]
- Naloxone in shock. Lancet. 1980 Dec 20;2(8208-8209):1360–1360. [PubMed] [Google Scholar]
- Persson L. A., Carlgren G. Measuring children's diets: evaluation of dietary assessment techniques in infancy and childhood. Int J Epidemiol. 1984 Dec;13(4):506–517. doi: 10.1093/ije/13.4.506. [DOI] [PubMed] [Google Scholar]
- Sorva R., Lankinen S., Tolppanen E. M., Perheentupa J. Variation of growth in height and weight of children. II. After infancy. Acta Paediatr Scand. 1990 May;79(5):498–506. doi: 10.1111/j.1651-2227.1990.tb11503.x. [DOI] [PubMed] [Google Scholar]
- Sorva R., Tolppanen E. M., Perheentupa J. Variation of growth in length and weight of children. I. Years 1 and 2. Acta Paediatr Scand. 1990 May;79(5):490–497. doi: 10.1111/j.1651-2227.1990.tb11502.x. [DOI] [PubMed] [Google Scholar]
- Stevens F. M., Egan-Mitchell B., Cryan E., McCarthy C. F., McNicholl B. Decreasing incidence of coeliac disease. Arch Dis Child. 1987 May;62(5):465–468. doi: 10.1136/adc.62.5.465. [DOI] [PMC free article] [PubMed] [Google Scholar]