Skip to main content
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1994 Sep;71(3):254–255. doi: 10.1136/adc.71.3.254

Detection of pneumocystis DNA in nasopharyngeal aspirates of leukaemic infants with pneumonia.

C G Richards 1, A E Wakefield 1, C D Mitchell 1
PMCID: PMC1029983  PMID: 7979502

Abstract

The technique of polymerase chain reaction was used to detect Pneumocystis carinii DNA in nasopharyngeal secretions of three infants with leukaemia who had the clinical features of P carinii pneumonia. The use of this non-invasive technique allowed the early diagnosis and treatment of these infants whose protocols did not include the use of prophylactic co-trimoxazole.

Full text

PDF
254

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Hague R. A., Burns S. E., Mok J. Y., Yap P. L. Diagnosis of Pneumocystis carinii pneumonia from non-invasive sampling of respiratory secretions. Arch Dis Child. 1990 Dec;65(12):1364–1365. doi: 10.1136/adc.65.12.1364. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Wakefield A. E., Guiver L., Miller R. F., Hopkin J. M. DNA amplification on induced sputum samples for diagnosis of Pneumocystis carinii pneumonia. Lancet. 1991 Jun 8;337(8754):1378–1379. doi: 10.1016/0140-6736(91)93062-e. [DOI] [PubMed] [Google Scholar]
  3. Wakefield A. E., Miller R. F., Guiver L. A., Hopkin J. M. Oropharyngeal samples for detection of Pneumocystis carinii by DNA amplification. Q J Med. 1993 Jun;86(6):401–406. [PubMed] [Google Scholar]
  4. Wakefield A. E., Pixley F. J., Banerji S., Sinclair K., Miller R. F., Moxon E. R., Hopkin J. M. Detection of Pneumocystis carinii with DNA amplification. Lancet. 1990 Aug 25;336(8713):451–453. doi: 10.1016/0140-6736(90)92008-6. [DOI] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES