Abstract
The technique of polymerase chain reaction was used to detect Pneumocystis carinii DNA in nasopharyngeal secretions of three infants with leukaemia who had the clinical features of P carinii pneumonia. The use of this non-invasive technique allowed the early diagnosis and treatment of these infants whose protocols did not include the use of prophylactic co-trimoxazole.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Hague R. A., Burns S. E., Mok J. Y., Yap P. L. Diagnosis of Pneumocystis carinii pneumonia from non-invasive sampling of respiratory secretions. Arch Dis Child. 1990 Dec;65(12):1364–1365. doi: 10.1136/adc.65.12.1364. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wakefield A. E., Guiver L., Miller R. F., Hopkin J. M. DNA amplification on induced sputum samples for diagnosis of Pneumocystis carinii pneumonia. Lancet. 1991 Jun 8;337(8754):1378–1379. doi: 10.1016/0140-6736(91)93062-e. [DOI] [PubMed] [Google Scholar]
- Wakefield A. E., Miller R. F., Guiver L. A., Hopkin J. M. Oropharyngeal samples for detection of Pneumocystis carinii by DNA amplification. Q J Med. 1993 Jun;86(6):401–406. [PubMed] [Google Scholar]
- Wakefield A. E., Pixley F. J., Banerji S., Sinclair K., Miller R. F., Moxon E. R., Hopkin J. M. Detection of Pneumocystis carinii with DNA amplification. Lancet. 1990 Aug 25;336(8713):451–453. doi: 10.1016/0140-6736(90)92008-6. [DOI] [PubMed] [Google Scholar]