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. 1994 Nov;71(5):398–403. doi: 10.1136/adc.71.5.398

Is the risk of cancer increased in Asians living in the UK?

J E Powell 1, S E Parkes 1, A H Cameron 1, J R Mann 1
PMCID: PMC1030049  PMID: 7826109

Abstract

The pattern of cancer in white and Asian (Indian, Pakistani, and Bangladeshi) children living in the West Midlands Health Authority Region was investigated using age standardised incidence rates. Two sets of rates were calculated, a 10 year rate (1982-91) using survey based estimates of the ethnic population and a four year rate (1989-92) using the ethnic population counts from the 1991 census. The 10 year rates showed a significantly higher annual incidence of cancer in Asian (159.1/million/year) than in white (130.8) children. The pattern of cancers in Asian children was different, with an excess of lymphomas and germ cell tumours, and a deficit of rhabdomyosarcomas. These findings were confirmed by the four year rates. Although underestimation of the Asian population probably contributes to the apparent excess, there remains cause for concern that UK Asian children may be at higher risk of cancer. Accurate ethnic population figures and confirmatory studies are urgently required.

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Selected References

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  1. Birch J. M., Marsden H. B. A classification scheme for childhood cancer. Int J Cancer. 1987 Nov 15;40(5):620–624. doi: 10.1002/ijc.2910400508. [DOI] [PubMed] [Google Scholar]
  2. Bundey S., Alam H., Kaur A., Mir S., Lancashire R. Why do UK-born Pakistani babies have high perinatal and neonatal mortality rates? Paediatr Perinat Epidemiol. 1991 Jan;5(1):101–114. doi: 10.1111/j.1365-3016.1991.tb00689.x. [DOI] [PubMed] [Google Scholar]
  3. Carr-Hill R. A. Underenumeration in 1991 census. Census inaccurate for many ethnic groups. BMJ. 1993 Dec 11;307(6918):1563–1564. doi: 10.1136/bmj.307.6918.1563-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Glover G. R. Sex ratio errors in census data. BMJ. 1993 Aug 21;307(6902):506–506. doi: 10.1136/bmj.307.6902.506-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Goodman M. T., Yoshizawa C. N., Kolonel L. N. Ethnic patterns of childhood cancer in Hawaii between 1960 and 1984. Cancer. 1989 Oct 15;64(8):1758–1763. doi: 10.1002/1097-0142(19891015)64:8<1758::aid-cncr2820640834>3.0.co;2-5. [DOI] [PubMed] [Google Scholar]
  6. Johnston H. E., Mann J. R., Williams J., Waterhouse J. A., Birch J. M., Cartwright R. A., Draper G. J., Hartley A. L., McKinney P. A., Hopton P. A. The Inter-Regional, Epidemiological Study of Childhood Cancer (IRESCC): case-control study in children with germ cell tumours. Carcinogenesis. 1986 May;7(5):717–722. doi: 10.1093/carcin/7.5.717. [DOI] [PubMed] [Google Scholar]
  7. Kramer S., Meadows A. T., Jarrett P., Evans A. E. Incidence of childhood cancer: experience of a decade in a population-based registry. J Natl Cancer Inst. 1983 Jan;70(1):49–55. [PubMed] [Google Scholar]
  8. Muir K. R., Parkes S. E., Mann J. R., Stevens M. C., Cameron A. H. Childhood cancer in the West Midlands: incidence and survival, 1980-1984, in a multi-ethnic population. Clin Oncol (R Coll Radiol) 1992 May;4(3):177–182. doi: 10.1016/s0936-6555(05)81083-0. [DOI] [PubMed] [Google Scholar]
  9. Parkes S. E., Coad N. A., Muir K. R., Jones T. J., Cameron A. H., Mann J. R. Hodgkin's disease in children in the West Midlands, 1957-1986: a large population-based study. Pediatr Hematol Oncol. 1994 Sep-Oct;11(5):471–486. doi: 10.3109/08880019409141686. [DOI] [PubMed] [Google Scholar]
  10. Stiller C. A., McKinney P. A., Bunch K. J., Bailey C. C., Lewis I. J. Childhood cancer and ethnic group in Britain: a United Kingdom children's Cancer Study Group (UKCCSG) study. Br J Cancer. 1991 Sep;64(3):543–548. doi: 10.1038/bjc.1991.347. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Thompson E. J. Underenumeration in the 1991 census. BMJ. 1993 Sep 25;307(6907):803–803. doi: 10.1136/bmj.307.6907.803-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Victor C. Underenumeration in 1991 census. Forms not retrieved. BMJ. 1993 Dec 11;307(6918):1564–1564. doi: 10.1136/bmj.307.6918.1564. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Vogel F. Genetics of retinoblastoma. Hum Genet. 1979 Nov 1;52(1):1–54. doi: 10.1007/BF00284597. [DOI] [PubMed] [Google Scholar]
  14. Young J. L., Jr, Ries L. G., Silverberg E., Horm J. W., Miller R. W. Cancer incidence, survival, and mortality for children younger than age 15 years. Cancer. 1986 Jul 15;58(2 Suppl):598–602. doi: 10.1002/1097-0142(19860715)58:2+<598::aid-cncr2820581332>3.0.co;2-c. [DOI] [PubMed] [Google Scholar]

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