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. 2023 Jun 16;28(12):4808. doi: 10.3390/molecules28124808

Figure 1.

Figure 1

Effects of L-proline supplementation on cell viability and NO release in BV2 microglia exposed to toxic concentrations of AZE. (A) Cell viability and (B) NO release in untreated, L-proline-, AZE- or AZE + L-proline-treated cells at 6 and 24 h, as determined by MTT and Griess assays. Results are reported as % of control. AZE and L-proline concentrations are indicated in the corresponding legends. Data shown as the mean ± SEM from two independent experiments, each using six batches of cells (n = 6). ** p < 0.01 and **** p < 0.0001 vs. control or # p < 0.05 and #### p < 0.0001 vs. AZE-treated cells, as determined by repeated measures ANOVA followed by Tukey post hoc test. NO = nitric oxide; Ctrl = control; Aze = L-azetidine-2-carboxylic acid.