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. 2023 Jun 1;15(6):1637. doi: 10.3390/pharmaceutics15061637

Table 2.

Equilibrium solubility of miconazole nitrate in the blank microemulsions at 30 ± 2 °C.

Sample Equilibrium Solubility a (%w/w)
Blank microemulsions
PSM:Ethanol (1:1) 1.560 ± 0.009
PSM:Ethanol (2:1) 1.450 ± 0.050
PSM:Ethanol (3:1) 1.062 ± 0.101
PSM:2-Propanol (1:1) 1.237 ± 0.025
PSM:2-Propanol (2:1) 1.290 ± 0.032
PSM:2-Propanol (3:1) 1.232 ± 0.095
PSM:2-(2-Ethoxyethoxy) ethanol (1:1) 1.384 ± 0.033
PSM: 2-(2-Ethoxyethoxy) ethanol (2:1) 1.069 ± 0.241
PSM: 2-(2-Ethoxyethoxy) ethanol (3:1) 1.068 ± 0.150
Deionized water 0.026 ± 0.001

PSM = polyoxyethylene sorbitan monooleate; a Values are shown as mean ± SD (n = 3).