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. 2023 Jun 1;15(6):1637. doi: 10.3390/pharmaceutics15061637

Table 4.

Constructed PLSR models with model parameters.

Data Pretreatment Factors R2 Model RMSEC R2 Pearson RMSEP Bias
Original 9 0.9845 0.0674 0.9861 0.0696 0.0106
First derivative 6 0.9844 0.0676 0.9790 0.0775 0.0042
Second derivative 6 0.9882 0.0589 0.9607 0.1122 −0.0237
Standard normal variate 5 0.9672 0.0980 0.9633 0.1074 −0.0149
Area normalization 6 0.9661 0.0997 0.9599 0.1118 −0.0314
Orthogonal signal correction 1 0.9919 0.0488 0.9958 0.0390 0.0061

RMSEC = root mean square error of calibration; RMSEP = root mean square error of prediction.