Error in Figure
In the original publication [1], there was a mistake in Figure 6A and Figure 7A as published. One sub-image in the replicates of negative control V1 was uploaded instead of V2. The corrected Figure 6 and Figure 7 appear below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
Figure 6.
Flow cytometric analysis of cell cycle distribution of PI-stained MCF-7 cells. (A) Representative flow cytometry histograms after treatment with V1, V2, raw 2ME, 2ME-SNEDDS, and DOX. (B) Cumulative bar chart showing the percentage of cells in the G0/G1, S, and G2/M phases of the cell cycle. (C) Graphic presentation of the percentages of cell cycle phases. Results are presented as mean ± SD (n = 6). * Significantly different from control at p < 0.05, # significantly different from V1 at p < 0.05, $ significantly different from V2 at p < 0.05, † significantly different from raw 2ME at p < 0.05, ‡ significantly different from 2ME-SNEDDS at p < 0.05.
Figure 7.
Flow cytometric analysis of early (lower left quadrant) and late apoptosis (lower right quadrant) and necrosis (upper right quadrant) using annexin V-FITC/PI double staining in MCF-7 cells following challenge with V1, V2, raw 2ME, 2ME-SNEDDS, and DOX. (A) Representative flow cytometric dot plots, (B) graphic presentation of early apoptosis, late apoptosis, necrosis, and total MCF-7 cells death. Results are presented as mean ± SD (n = 6). * Significantly different from control at p < 0.05, # significantly different from V1 at p < 0.05, $ significantly different from V2 at p < 0.05, † significantly different from raw 2ME at p < 0.05, ‡ significantly different from 2ME-SNEDDS at p < 0.05.
Footnotes
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Reference
- 1.Al-Qahtani S.D., Bin-Melaih H.H., Atiya E.M., Fahmy U.A., Binmahfouz L.S., Neamatallah T., Al-Abbasi F.A., Abdel-Naim A.B. Self-Nanoemulsifying Drug Delivery System of 2-Methoxyestradiol Exhibits Enhanced Anti-Proliferative and Pro-Apoptotic Activities in MCF-7 Breast Cancer Cells. Life. 2022;12:1369. doi: 10.3390/life12091369. [DOI] [PMC free article] [PubMed] [Google Scholar]