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. 2023 Jun 8;13(6):1343. doi: 10.3390/life13061343

Correction: Al-Qahtani et al. Self-Nanoemulsifying Drug Delivery System of 2-Methoxyestradiol Exhibits Enhanced Anti-Proliferative and Pro-Apoptotic Activities in MCF-7 Breast Cancer Cells. Life 2022, 12, 1369

Salwa D Al-Qahtani 1,2, Hawazen H Bin-Melaih 3, Eman M Atiya 2, Usama A Fahmy 4, Lenah S Binmahfouz 5, Thikryat Neamatallah 5, Fahad A Al-Abbasi 2, Ashraf B Abdel-Naim 5,*
PMCID: PMC10305199  PMID: 37374204

Error in Figure

In the original publication [1], there was a mistake in Figure 6A and Figure 7A as published. One sub-image in the replicates of negative control V1 was uploaded instead of V2. The corrected Figure 6 and Figure 7 appear below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Figure 6.

Figure 6

Flow cytometric analysis of cell cycle distribution of PI-stained MCF-7 cells. (A) Representative flow cytometry histograms after treatment with V1, V2, raw 2ME, 2ME-SNEDDS, and DOX. (B) Cumulative bar chart showing the percentage of cells in the G0/G1, S, and G2/M phases of the cell cycle. (C) Graphic presentation of the percentages of cell cycle phases. Results are presented as mean ± SD (n = 6). * Significantly different from control at p < 0.05, # significantly different from V1 at p < 0.05, $ significantly different from V2 at p < 0.05, † significantly different from raw 2ME at p < 0.05, ‡ significantly different from 2ME-SNEDDS at p < 0.05.

Figure 7.

Figure 7

Flow cytometric analysis of early (lower left quadrant) and late apoptosis (lower right quadrant) and necrosis (upper right quadrant) using annexin V-FITC/PI double staining in MCF-7 cells following challenge with V1, V2, raw 2ME, 2ME-SNEDDS, and DOX. (A) Representative flow cytometric dot plots, (B) graphic presentation of early apoptosis, late apoptosis, necrosis, and total MCF-7 cells death. Results are presented as mean ± SD (n = 6). * Significantly different from control at p < 0.05, # significantly different from V1 at p < 0.05, $ significantly different from V2 at p < 0.05, † significantly different from raw 2ME at p < 0.05, ‡ significantly different from 2ME-SNEDDS at p < 0.05.

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Reference

  • 1.Al-Qahtani S.D., Bin-Melaih H.H., Atiya E.M., Fahmy U.A., Binmahfouz L.S., Neamatallah T., Al-Abbasi F.A., Abdel-Naim A.B. Self-Nanoemulsifying Drug Delivery System of 2-Methoxyestradiol Exhibits Enhanced Anti-Proliferative and Pro-Apoptotic Activities in MCF-7 Breast Cancer Cells. Life. 2022;12:1369. doi: 10.3390/life12091369. [DOI] [PMC free article] [PubMed] [Google Scholar]

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