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a-c) Phylogenetic trees of human, chimpanzee, orangutan, and macaque α-satellites from the higher-order and monomeric α-satellite regions of the chromosome 5, 12, and X centromeres, respectively. d-f) Plot showing the mutation rate of the chromosome 5, 12, and X centromeric regions, respectively. Individual data points from 10 kbp pairwise sequence alignments are shown.
