Skip to main content
PMC home page
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1970 Jul;29(4):434–438. doi: 10.1136/ard.29.4.434

Leucineaminopeptidase in rheumatoid arthritis. Localization in subchondral bone and in synovial fluid cells.

U Vainio
PMCID: PMC1031330  PMID: 5454281

Full text

PDF
434

Images in this article

435Image
on p.435
435Image
on p.435
435Image
on p.435
435Image
on p.435
436Image
on p.436
436Image
on p.436
436Image
on p.436
436Image
on p.436

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ali S. Y. The degradation of cartilage matrix by an intracellular protease. Biochem J. 1964 Dec;93(3):611–618. doi: 10.1042/bj0930611. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BARLAND P., NOVIKOFF A. B., HAMERMAN D. FINE STRUCTURE AND CYTOCHEMISTRY OF THE RHEUMATOID SYNOVIAL MEMBRANE, WITH SPECIAL REFERENCE TO LYSOSOMES. Am J Pathol. 1964 May;44:853–866. [PMC free article] [PubMed] [Google Scholar]
  3. BURSTONE M. S. Histochemical demonstration of proteolytic activity in human neoplasms. J Natl Cancer Inst. 1956 Apr;16(5):1149–1161. [PubMed] [Google Scholar]
  4. DIAGNOSTIC criteria for rheumatoid arthritis: 1958 revision by a committee of the American Rheumatism Association. Ann Rheum Dis. 1959 Mar;18(1):49–53. [PMC free article] [PubMed] [Google Scholar]
  5. GLENNER G. G., BURSTONE M. S., MEYER D. B. A study of aminopeptidase activity in the stroma of neoplastic tissue, with a comparison of histochemical techniques. J Natl Cancer Inst. 1959 Oct;23:857–873. [PubMed] [Google Scholar]
  6. HOLLANDER J. L., MCCARTY D. J., Jr, ASTORGA G., CASTRO-MURILLO E. STUDIES ON THE PATHOGENESIS OF RHEUMATOID JOINT INFLAMMATION. I. THE "R.A. CELL" AND A WORKING HYPOTHESIS. Ann Intern Med. 1965 Feb;62:271–280. doi: 10.7326/0003-4819-62-2-271. [DOI] [PubMed] [Google Scholar]
  7. HUETTL S., MARKOVIC O. AMINOTRIPEPTID'AZOV'A AKTIVITA SYNOVI'ALNEHO V'YPOTKU. I. Bratisl Lek Listy. 1963;43:585–596. [PubMed] [Google Scholar]
  8. LEVER J. D., FORD E. H. Histological, histochemical and electron microscopic observations on synovial membrane. Anat Rec. 1958 Dec;132(4):525–539. doi: 10.1002/ar.1091320402. [DOI] [PubMed] [Google Scholar]
  9. LIPP W. Aminopeptidase in bone cells. J Histochem Cytochem. 1959 May;7(3):205–205. doi: 10.1177/7.3.205. [DOI] [PubMed] [Google Scholar]
  10. LUSCOMBE M. Acid phosphatase and catheptic activity in rheumatoid synovial tissue. Nature. 1963 Mar 9;197:1010–1010. doi: 10.1038/1971010a0. [DOI] [PubMed] [Google Scholar]
  11. NACHLAS M. M., CRAWFORD D. T., SELIGMAN A. M. The histochemical demonstration of leucine aminopeptidase. J Histochem Cytochem. 1957 May;5(3):264–278. doi: 10.1177/5.3.264. [DOI] [PubMed] [Google Scholar]
  12. PEARSE A. G., TREMBLAY G. Leucine aminopeptidase in rat parathyroid and its relation to parathyroid hormone production. Nature. 1958 May 31;181(4622):1532–1533. doi: 10.1038/1811532a0. [DOI] [PubMed] [Google Scholar]
  13. RAWSON A. J., ABELSON N. M., HOLLANDER J. L. STUDIES ON THE PATHOGENESIS OF RHEUMATOID JOINT INFLAMMATION. II. INTRACYTOPLASMIC PARTICULATE COMPLEXES IN RHEUMATOID SYNOVIAL FLUIDS. Ann Intern Med. 1965 Feb;62:281–284. doi: 10.7326/0003-4819-62-2-281. [DOI] [PubMed] [Google Scholar]
  14. RESTIFO R. A., LUSSIER A. J., RAWSON A. J., ROCKEY J. H., HOLLANDER J. L. STUDIES ON THE PATHOGENESIS OF RHEUMATOID JOINT INFLAMMATION. 3. THE EXPERIMENTAL PRODUCTION OF ARTHRITIS BY THE INTRA-ARTICULAR INJECTION OF PURIFIED 7S GAMMA GLOBULIN. Ann Intern Med. 1965 Feb;62:285–291. doi: 10.7326/0003-4819-62-2-285. [DOI] [PubMed] [Google Scholar]
  15. Vainio U. A histochemical study on leucinoaminopeptidase activity in the synovial membrane of patients with rheumatoid arthritis. Ann Rheum Dis. 1966 May;25(3):253–258. doi: 10.1136/ard.25.3.253. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. WEISSMANN G., THOMAS L. Studies on lysosomes. II. The effect of cortisone on the release of acid hydrolases from a large granule fraction of rabbit liver induced by an excess of vitamin A. J Clin Invest. 1963 May;42:661–669. doi: 10.1172/JCI104757. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Wegelius O., Klockars M., Vainio K. Acid phosphatase activity in rheumatoid synovia. Acta Med Scand. 1968 Jun;183(6):549–551. doi: 10.1111/j.0954-6820.1968.tb10521.x. [DOI] [PubMed] [Google Scholar]
  18. Weissmann G., Spilberg I. Breakdown of cartilage proteinpolysaccharide by lysosomes. Arthritis Rheum. 1968 Apr;11(2):162–169. doi: 10.1002/art.1780110206. [DOI] [PubMed] [Google Scholar]
  19. ZIFF M., GRIBETZ H. J., LOSPALLUTO J. Effect of leukocyte and synovial membrane extracts on cartilage mucoprotein. J Clin Invest. 1960 Feb;39:405–412. doi: 10.1172/JCI104051. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. ZIFF M., SIMSON J., SCULL E., SMITH A., SHATTON J., MAINLAND D. Aminotripeptidase content of synovial fluid in arthritic diseases. J Clin Invest. 1955 Jan;34(1):27–34. doi: 10.1172/JCI103059. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES