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. 1987 Feb;50(2):194–198. doi: 10.1136/jnnp.50.2.194

Controlled release levodopa treatment of motor fluctuations in Parkinson's disease.

J L Juncos, G Fabbrini, M M Mouradian, C Serrati, A M Kask, T N Chase
PMCID: PMC1031491  PMID: 3572434

Abstract

A controlled release preparation of levodopa-carbidopa, CR III, given every 4 hours to 17 Parkinsonian patients for up to 10 months reduced plasma drug variations and improved motor response fluctuations compared with standard levodopa-carbidopa given every 2 hours. The results support the value of pharmaceutical approaches to the stabilisation of circulating levodopa levels in the treatment of Parkinson's disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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