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. 1987 Feb;50(2):224–227. doi: 10.1136/jnnp.50.2.224

Necrotising haemorrhagic encephalomyelopathy in an adult: Leigh's disease.

G Delgado, J Gállego, T Tuñón, J J Zarranz, J A Villanueva
PMCID: PMC1031497  PMID: 3572437

Abstract

A 21 year old male, well-nourished and non-alcoholic, died after five weeks illness. He had suffered epileptic fits, bilateral internuclear ophthalmoplegia, bulbar and pontine paralysis, tetraparesia, ataxia and dystonia. A CT brain scan showed low density lesions of the striatum bilaterally. Post-mortem studies revealed pathological anomalies compatible with Leigh's disease, although the presence of haemorrhages and involvement of the mamillary bodies could also suggest Wernicke's encephalopathy.

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Selected References

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