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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1988 Feb;51(2):277–280. doi: 10.1136/jnnp.51.2.277

Multiple sclerosis: correlation of magnetic resonance imaging with cerebrospinal fluid findings.

L S Honig 1, R Siddharthan 1, W A Sheremata 1, J J Sheldon 1, A Sazant 1
PMCID: PMC1031544  PMID: 2450176

Abstract

MRI examination of 41 patients with clinical definite multiple sclerosis showed white matter lesions of high proton T2 signal consistent with demyelination in 76% and CSF abnormalities present in 76%. Of patients with CSF abnormalities, 26% had normal MRI scans; conversely 26% of patients with MRI abnormalities had negative CSF studies. Thus a significant number of multiple sclerosis patients had negative results on either MRI or CSF examination, while only 5% had normal results on both tests.

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Selected References

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