Skip to main content
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1989 Dec;52(12):1364–1368. doi: 10.1136/jnnp.52.12.1364

Pattern electroretinography in patients with delayed pattern visual evoked potentials due to distal anterior visual pathway dysfunction.

G E Holder 1
PMCID: PMC1031593  PMID: 2614431

Abstract

Between March 1983 and January 1988 delayed pattern visual evoked potentials (PVEP) were observed in 67 patients with distal visual pathway dysfunction. Many of these patients had been referred for neurophysiological examination because of possible optic nerve dysfunction. These patients also had pattern electroretinography (PERG) performed which in all cases showed an abnormality of the main positive P50 component. None of these patients had an abnormality confined to the negative N95 component, the type of abnormality usually found if the PERG is abnormal in optic nerve disease. It is suggested that PERG recording should now be a routine adjunct to the PVEP in the assessment of anterior visual pathway dysfunction.

Full text

PDF
1364

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arden G. B., Vaegan, Hogg C. R., Powell D. J., Carter R. M. Pattern ERGs are abnormal in many amblyopes. Trans Ophthalmol Soc U K. 1980;100(4):453–460. [PubMed] [Google Scholar]
  2. Arden G. B., Wooding S. L. Pattern ERG in amblyopia. Invest Ophthalmol Vis Sci. 1985 Jan;26(1):88–96. [PubMed] [Google Scholar]
  3. Asselman P., Chadwick D. W., Marsden D. C. Visual evoked responses in the diagnosis and management of patients suspected of multiple sclerosis. Brain. 1975 Jun;98(2):261–282. doi: 10.1093/brain/98.2.261. [DOI] [PubMed] [Google Scholar]
  4. Bass S. J., Sherman J., Bodis-Wollner I., Nath S. Visual evoked potentials in macular disease. Invest Ophthalmol Vis Sci. 1985 Aug;26(8):1071–1074. [PubMed] [Google Scholar]
  5. Berninger T., Schuurmans R. P. Spatial tuning of the pattern ERG across temporal frequency. Doc Ophthalmol. 1985 Oct 30;61(1):17–25. doi: 10.1007/BF00143211. [DOI] [PubMed] [Google Scholar]
  6. Blakemore C., Van Sluyters R. C. Innate and environmental factors in the development of the kitten's visual cortex. J Physiol. 1975 Jul;248(3):663–716. doi: 10.1113/jphysiol.1975.sp010995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Celesia G. G., Kaufman D. Pattern ERGs and visual evoked potentials in maculopathies and optic nerve diseases. Invest Ophthalmol Vis Sci. 1985 May;26(5):726–735. [PubMed] [Google Scholar]
  8. Cleland B. G., Crewther D. P., Crewther S. G., Mitchell D. E. Normality of spatial resolution of retinal ganglion cells in cats with strabismic amblyopia. J Physiol. 1982 May;326:235–249. doi: 10.1113/jphysiol.1982.sp014188. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Gottlob I., Welge-Lüssen L. Normal pattern electroretinograms in amblyopia. Invest Ophthalmol Vis Sci. 1987 Jan;28(1):187–191. [PubMed] [Google Scholar]
  10. Hess R. F., Baker C. L., Jr, Verhoeve J. N., Keesey U. T., France T. D. The pattern evoked electroretinogram: its variability in normals and its relationship to amblyopia. Invest Ophthalmol Vis Sci. 1985 Nov;26(11):1610–1623. [PubMed] [Google Scholar]
  11. Holder G. E. Pattern visual evoked potential in patients with posteriorly situated space-occupying lesions. Doc Ophthalmol. 1985 Feb;59(2):121–128. doi: 10.1007/BF00160608. [DOI] [PubMed] [Google Scholar]
  12. Holder G. E. Significance of abnormal pattern electroretinography in anterior visual pathway dysfunction. Br J Ophthalmol. 1987 Mar;71(3):166–171. doi: 10.1136/bjo.71.3.166. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Holder G. E. The effects of chiasmal compression on the pattern visual evoked potential. Electroencephalogr Clin Neurophysiol. 1978 Aug;45(2):278–280. doi: 10.1016/0013-4694(78)90011-1. [DOI] [PubMed] [Google Scholar]
  14. Hubel D. H., Wiesel T. N. Binocular interaction in striate cortex of kittens reared with artificial squint. J Neurophysiol. 1965 Nov;28(6):1041–1059. doi: 10.1152/jn.1965.28.6.1041. [DOI] [PubMed] [Google Scholar]
  15. Ikeda H., Tremain K. E. Amblyopia occurs in retinal ganglion cells in cats reared with convergent squint without alternating fixation. Exp Brain Res. 1979 May 2;35(3):559–582. doi: 10.1007/BF00236772. [DOI] [PubMed] [Google Scholar]
  16. Ikeda H., Tremain K. E. Amblyopia resulting from penalisation: neurophysiological studies of kittens reared with atropinisation of one or both eyes. Br J Ophthalmol. 1978 Jan;62(1):21–28. doi: 10.1136/bjo.62.1.21. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Ikeda H. Visual acuity, its development and amblyopia. J R Soc Med. 1980 Aug;73(8):546–555. doi: 10.1177/014107688007300803. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Kirkham T. H., Coupland S. G. The pattern electroretinogram in optic nerve demyelination. Can J Neurol Sci. 1983 Nov;10(4):256–260. doi: 10.1017/s031716710004511x. [DOI] [PubMed] [Google Scholar]
  19. Lennerstrand G. Delayed visual evoked cortical potentials in retinal disease. Acta Ophthalmol (Copenh) 1982 Aug;60(4):497–504. doi: 10.1111/j.1755-3768.1982.tb00594.x. [DOI] [PubMed] [Google Scholar]
  20. Mastaglia F. L., Black J. L., Cala L. A., Collins D. W. Electrophysiology and avoidance of invasive neuroradiology in multiple sclerosis. Lancet. 1980 Jan 19;1(8160):144–144. doi: 10.1016/s0140-6736(80)90618-2. [DOI] [PubMed] [Google Scholar]
  21. Ota I., Miyake Y. The pattern electroretinogram in patients with optic nerve disease. Doc Ophthalmol. 1986 Jan 31;62(1):53–59. doi: 10.1007/BF00140547. [DOI] [PubMed] [Google Scholar]
  22. Papakostopoulos D., Hart C. D., Cooper R., Natsikos V. Combined electrophysiological assessment of the visual system in central serous retinopathy. Electroencephalogr Clin Neurophysiol. 1984 Feb;59(1):77–80. doi: 10.1016/0168-5597(84)90023-6. [DOI] [PubMed] [Google Scholar]
  23. Persson H. E., Wanger P. Pattern-reversal electroretinograms and visual evoked cortical potentials in multiple sclerosis. Br J Ophthalmol. 1984 Oct;68(10):760–764. doi: 10.1136/bjo.68.10.760. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Persson H. E., Wanger P. Pattern-reversal electroretinograms in squint amblyopia, artificial anisometropia and simulated eccentric fixation. Acta Ophthalmol (Copenh) 1982 Feb;60(1):123–132. doi: 10.1111/j.1755-3768.1982.tb05788.x. [DOI] [PubMed] [Google Scholar]
  25. Plant G. T., Hess R. F., Thomas S. J. The pattern evoked electroretinogram in optic neuritis. A combined psychophysical and electrophysiological study. Brain. 1986 Jun;109(Pt 3):469–490. doi: 10.1093/brain/109.3.469. [DOI] [PubMed] [Google Scholar]
  26. Ryan S., Arden G. B. Electrophysiological discrimination between retinal and optic nerve disorders. Doc Ophthalmol. 1988 Mar-Apr;68(3-4):247–255. doi: 10.1007/BF00156431. [DOI] [PubMed] [Google Scholar]
  27. Sanders M. D. Diagnostic difficulties in optic nerve disease and in papilloedema and disc oedema. Trans Ophthalmol Soc U K. 1976 Sep;96(3):386–394. [PubMed] [Google Scholar]
  28. Serra G., Carreras M., Tugnoli V., Manca M., Cristofori M. C. Pattern electroretinogram in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1984 Aug;47(8):879–883. doi: 10.1136/jnnp.47.8.879. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Sokol S., Nadler D. Simultaneous electroretinograms and visually evoked potentials from adult amblyopes in response to a pattern stimulus. Invest Ophthalmol Vis Sci. 1979 Aug;18(8):848–855. [PubMed] [Google Scholar]
  30. Tan C. B., King P. J., Chiappa K. H. Pattern ERG: effects of reference electrode site, stimulus mode and check size. Electroencephalogr Clin Neurophysiol. 1989 Jan-Feb;74(1):11–18. doi: 10.1016/0168-5597(89)90046-4. [DOI] [PubMed] [Google Scholar]
  31. Wanger P., Persson H. E. Pattern-reversal electroretinograms in unilateral glaucoma. Invest Ophthalmol Vis Sci. 1983 Jun;24(6):749–753. [PubMed] [Google Scholar]
  32. Weinstein G. W., Arden G. B., Hitchings R. A., Ryan S., Calthorpe C. M., Odom J. V. The pattern electroretinogram (PERG) in ocular hypertension and glaucoma. Arch Ophthalmol. 1988 Jul;106(7):923–928. doi: 10.1001/archopht.1988.01060140069027. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES