Skip to main content
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1989 Nov;52(11):1273–1276. doi: 10.1136/jnnp.52.11.1273

Epileptic seizures in intracerebral haemorrhage.

C Y Sung 1, N S Chu 1
PMCID: PMC1031636  PMID: 2512371

Abstract

Among 1402 patients with intracerebral haemorrhage (ICH), seizures occurred in 64 (4.6%) and epilepsy in 35 (2.5%). Seizure was the first manifestation of ICH in 19 patients (30%). Status epilepticus occurred in 11 patients (17%) and it was the initial presentation of ICH in six (9%). The majority had simple partial seizures that were predominantly focal and motor. There were 38 patients with early seizure and 26 patients with late seizure. Ninety per cent of seizures occurred within one year after ICH. Eleven patients (29%) with early seizure developed epilepsy, whereas 24 patients (93%) with late seizure developed recurrent seizures. The incidence of seizure was 32% for lobar haematoma, 2% respectively for putaminal, thalamic and pontine haemorrhages and 1% for cerebellar haemorrhage. Twenty-six (62%) out of 42 patients with lobar haematomas developed epilepsy. Thirteen patients (34%) with early seizure died within three months after the onset of seizures whereas three patients (12%) with late seizure died within the same period. The majority of patients who died had deep-seated haematomas.

Full text

PDF
1273

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Annegers J. F., Grabow J. D., Groover R. V., Laws E. R., Jr, Elveback L. R., Kurland L. T. Seizures after head trauma: a population study. Neurology. 1980 Jul;30(7 Pt 1):683–689. doi: 10.1212/wnl.30.7.683. [DOI] [PubMed] [Google Scholar]
  2. Berger A. R., Lipton R. B., Lesser M. L., Lantos G., Portenoy R. K. Early seizures following intracerebral hemorrhage: implications for therapy. Neurology. 1988 Sep;38(9):1363–1365. doi: 10.1212/wnl.38.9.1363. [DOI] [PubMed] [Google Scholar]
  3. Caveness W. F., Meirowsky A. M., Rish B. L., Mohr J. P., Kistler J. P., Dillon J. D., Weiss G. H. The nature of posttraumatic epilepsy. J Neurosurg. 1979 May;50(5):545–553. doi: 10.3171/jns.1979.50.5.0545. [DOI] [PubMed] [Google Scholar]
  4. Celesia G. G. Modern concepts of status epilepticus. JAMA. 1976 Apr 12;235(15):1571–1574. [PubMed] [Google Scholar]
  5. DODGE P. R., RICHARDSON E. P., Jr, VICTOR M. Recurrent convulsive seizures as a sequel to cerebral infarction: a clinical and pathological study. Brain. 1954 Dec;77(4):610–638. doi: 10.1093/brain/77.4.610. [DOI] [PubMed] [Google Scholar]
  6. Fentz V. Epileptiske anfaldsfaenomener hos patienter med apoplexia cerebri. Nord Med. 1971 Sep 2;86(35):1023–1025. [PubMed] [Google Scholar]
  7. Harrison M. J. Clinical distinction of cerebral haemorrhage and cerebral infarction. Postgrad Med J. 1980 Sep;56(659):629–632. doi: 10.1136/pgmj.56.659.629. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. JANZ D. Conditions and causes of status epilepticus. Epilepsia. 1961 Jun;2:170–177. [PubMed] [Google Scholar]
  9. Lesser R. P., Lüders H., Dinner D. S., Morris H. H. Epileptic seizures due to thrombotic and embolic cerebrovascular disease in older patients. Epilepsia. 1985 Nov-Dec;26(6):622–630. doi: 10.1111/j.1528-1157.1985.tb05702.x. [DOI] [PubMed] [Google Scholar]
  10. Lipton R. B., Berger A. R., Lesser M. L., Lantos G., Portenoy R. K. Lobar vs thalamic and basal ganglion hemorrhage: clinical and radiographic features. J Neurol. 1987 Feb;234(2):86–90. doi: 10.1007/BF00314107. [DOI] [PubMed] [Google Scholar]
  11. Louis S., McDowell F. Epileptic seizures in nonembolic cerebral infarction. Arch Neurol. 1967 Oct;17(4):414–418. doi: 10.1001/archneur.1967.00470280080008. [DOI] [PubMed] [Google Scholar]
  12. Mohr J. P., Caplan L. R., Melski J. W., Goldstein R. J., Duncan G. W., Kistler J. P., Pessin M. S., Bleich H. L. The Harvard Cooperative Stroke Registry: a prospective registry. Neurology. 1978 Aug;28(8):754–762. doi: 10.1212/wnl.28.8.754. [DOI] [PubMed] [Google Scholar]
  13. Olsen T. S., Høgenhaven H., Thage O. Epilepsy after stroke. Neurology. 1987 Jul;37(7):1209–1211. doi: 10.1212/wnl.37.7.1209. [DOI] [PubMed] [Google Scholar]
  14. Oxbury J. M., Whitty C. W. Causes and consequences of status epilepticus in adults. A study of 86 cases. Brain. 1971;94(4):733–744. doi: 10.1093/brain/94.4.733. [DOI] [PubMed] [Google Scholar]
  15. Oxbury J. M., Whitty C. W. The syndrome of isolated epileptic status. J Neurol Neurosurg Psychiatry. 1971 Apr;34(2):182–184. doi: 10.1136/jnnp.34.2.182. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. RICHARDSON E. P., Jr, DODGE P. R. Epilepsy in cerebral vascular disease; a study of the incidence and nature of seizures in 104 consecutive autopsy-proven cases of cerebral infarction and hemorrhage. Epilepsia. 1954 Nov;3:49–74. doi: 10.1111/j.1528-1157.1954.tb03153.x. [DOI] [PubMed] [Google Scholar]
  17. Schaafsma S. On the differential diagnosis between cerebral haemorrhage and infarction. J Neurol Sci. 1968 Jul-Aug;7(1):83–95. doi: 10.1016/0022-510x(68)90005-1. [DOI] [PubMed] [Google Scholar]
  18. Schold C., Yarnell P. R., Earnest M. P. Origin of seizures in elderly patients. JAMA. 1977 Sep 12;238(11):1177–1178. [PubMed] [Google Scholar]
  19. Weisberg L. A. Computerized tomography in intracranial hemorrhage. Arch Neurol. 1979 Jul;36(7):422–426. doi: 10.1001/archneur.1979.00500430052007. [DOI] [PubMed] [Google Scholar]
  20. Weisberg L. A. Subcortical lobar intracerebral haemorrhage: clinical-computed tomographic correlations. J Neurol Neurosurg Psychiatry. 1985 Nov;48(11):1078–1084. doi: 10.1136/jnnp.48.11.1078. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES