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. 1987 Mar;50(3):327–332. doi: 10.1136/jnnp.50.3.327

Multiple sclerosis among the United Kingdom-born children of immigrants from the West Indies.

M Elian, G Dean
PMCID: PMC1031798  PMID: 3559614

Abstract

Multiple sclerosis has been reported to be very uncommon in the West Indies. In previous studies immigrants from the West Indies resident in Greater London had only one-eighth the likelihood of being diagnosed in hospital as having multiple sclerosis compared with those born in the United Kingdom. No studies of the incidence and prevalence of multiple sclerosis were available for London or South East England but there is evidence that it is much the same as occurs in Ireland. In the age groups studied the United Kingdom-born children of West Indian immigrants had an incidence and prevalence of probable multiple sclerosis of the same order as has been reported in Northern Ireland and in the Irish Republic. Although there is evidence that genetic factors play a part, our findings are strong evidence that the cause of the disease is mainly environmental and is therefore potentially preventable.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alter M., Kahana E., Loewenson R. Migration and risk of multiple sclerosis. Neurology. 1978 Nov;28(11):1089–1093. doi: 10.1212/wnl.28.11.1089. [DOI] [PubMed] [Google Scholar]
  2. Brady R., Dean G., Secerbegovic S., Secerbegovic A. M. Multiple sclerosis in the Republic of Ireland. Ir Med J. 1977 Nov 18;70(17):500–506. [PubMed] [Google Scholar]
  3. CRUICKSHANK E. K., MONTGOMERY R. D., SPILLANE J. D. Obscure neurologic disorders in Jamaica. World Neurol. 1961 Mar;2:199–211. [PubMed] [Google Scholar]
  4. Dean G. Annual incidence, prevalence, and mortality of multiple sclerosis in white South-African-born and in white immigrants to South Africa. Br Med J. 1967 Jun 17;2(5554):724–730. doi: 10.1136/bmj.2.5554.724. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Dean G., Brady R., McLoughlin H. Motor neurone disease and multiple sclerosis among immigrants to Britain. Br J Prev Soc Med. 1977 Sep;31(3):141–147. doi: 10.1136/jech.31.3.141. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Dean G., Grimaldi G., Kelly R., Karhausen L. Multiple sclerosis in southern Europe. I: Prevalence in Sicily in 1975. J Epidemiol Community Health. 1979 Jun;33(2):107–110. doi: 10.1136/jech.33.2.107. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Dean G., McDougall E. I., Elian M. Multiple sclerosis in research workers studying swayback in lambs: an updated report. J Neurol Neurosurg Psychiatry. 1985 Sep;48(9):859–865. doi: 10.1136/jnnp.48.9.859. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Dean G., McLoughlin H., Brady R., Adelstein A. M., Tallett-Williams J. Multiple sclerosis among immigrants in Greater London. Br Med J. 1976 Apr 10;1(6014):861–864. doi: 10.1136/bmj.1.6014.861. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Kurtzke J. F., Beebe G. W., Norman J. E., Jr Epidemiology of multiple sclerosis in U.S. veterans: 1. Race, sex, and geographic distribution. Neurology. 1979 Sep;29(9 Pt 1):1228–1235. doi: 10.1212/wnl.29.9_part_1.1228. [DOI] [PubMed] [Google Scholar]
  10. Kurtzke J. F., Hyllested K. Multiple sclerosis in the Faroe Islands: I. Clinical and epidemiological features. Ann Neurol. 1979 Jan;5(1):6–21. doi: 10.1002/ana.410050104. [DOI] [PubMed] [Google Scholar]
  11. Kurtzke J. F. Multiple sclerosis among immigrants. Br Med J. 1976 Jun 19;1(6024):1527–1528. doi: 10.1136/bmj.1.6024.1527-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Morganti G., Naccarato S., Elian M., Ferrari P., Kelly R., Karhausen L., Dean G. Multiple sclerosis in the Republic of San Marino. J Epidemiol Community Health. 1984 Mar;38(1):23–28. doi: 10.1136/jech.38.1.23. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Norman J. E., Jr, Kurtzke J. F., Beebe G. W. Epidemiology of multiple sclerosis in U.S. veterans: 2. Latitude, climate and the risk of multiple sclerosis. J Chronic Dis. 1983;36(8):551–559. doi: 10.1016/0021-9681(83)90142-x. [DOI] [PubMed] [Google Scholar]
  14. Savettieri G., Elian M., Giordano D., Grimaldi G., Ventura A., Dean G. A further study on the prevalence of multiple sclerosis in Sicily: Caltanissetta city. Acta Neurol Scand. 1986 Jan;73(1):71–75. doi: 10.1111/j.1600-0404.1986.tb03243.x. [DOI] [PubMed] [Google Scholar]
  15. Shepherd D. I., Downie A. W. A further prevalence study of multiple sclerosis in north-east Scotland. J Neurol Neurosurg Psychiatry. 1980 Apr;43(4):310–315. doi: 10.1136/jnnp.43.4.310. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Williams E. S., McKeran R. O. Prevalence of multiple sclerosis in a south London borough. Br Med J (Clin Res Ed) 1986 Jul 26;293(6541):237–239. doi: 10.1136/bmj.293.6541.237. [DOI] [PMC free article] [PubMed] [Google Scholar]

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