Skip to main content
NCBI home page
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1987 Jun;50(6):732–737. doi: 10.1136/jnnp.50.6.732

Stimulation of motor tracts in motor neuron disease.

A Berardelli, M Inghilleri, R Formisano, N Accornero, M Manfredi
PMCID: PMC1032079  PMID: 3612154

Abstract

The muscle responses evoked by cortical and cervical stimulation in 11 patients with motor neuron disease were studied. The muscle potential in the abductor pollicis brevis, evoked by median nerve stimulation and the somatosensory potential evoked by wrist stimulation were also studied. In eight of 11 patients there was absence or increased central delay of the responses evoked by cortical stimulation. In four patients muscle responses on cervical stimulation and muscle action potentials on median nerve stimulation were also altered, indicating peripheral abnormalities. Somatosensory responses evoked by wrist stimulation were normal. Electrophysiological techniques are helpful in estimating the site of motor involvement in motor neuron disease.

Full text

PDF
732

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bradley W. G., Good P., Rasool C. G., Adelman L. S. Morphometric and biochemical studies of peripheral nerves in amyotrophic lateral sclerosis. Ann Neurol. 1983 Sep;14(3):267–277. doi: 10.1002/ana.410140304. [DOI] [PubMed] [Google Scholar]
  2. Cowan J. M., Rothwell J. C., Dick J. P., Thompson P. D., Day B. L., Marsden C. D. Abnormalities in central motor pathway conduction in multiple sclerosis. Lancet. 1984 Aug 11;2(8398):304–307. doi: 10.1016/s0140-6736(84)92683-7. [DOI] [PubMed] [Google Scholar]
  3. Dick J. P., Cowan J. M., Day B. L., Berardelli A., Kachi T., Rothwell J. C., Marsden C. D. The corticomotoneurone connection is normal in Parkinson's disease. Nature. 1984 Aug 2;310(5976):407–409. doi: 10.1038/310407a0. [DOI] [PubMed] [Google Scholar]
  4. GILLIATT R. W., WILLISON R. G. Peripheral nerve conduction in diabetic neuropathy. J Neurol Neurosurg Psychiatry. 1962 Feb;25:11–18. doi: 10.1136/jnnp.25.1.11. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Levy W. J., York D. H., McCaffrey M., Tanzer F. Motor evoked potentials from transcranial stimulation of the motor cortex in humans. Neurosurgery. 1984 Sep;15(3):287–302. doi: 10.1227/00006123-198409000-00001. [DOI] [PubMed] [Google Scholar]
  6. Matheson J. K., Harrington H. J., Hallett M. Abnormalities of multimodality evoked potentials in amyotrophic lateral sclerosis. Arch Neurol. 1986 Apr;43(4):338–340. doi: 10.1001/archneur.1986.00520040026013. [DOI] [PubMed] [Google Scholar]
  7. Merton P. A., Hill D. K., Morton H. B., Marsden C. D. Scope of a technique for electrical stimulation of human brain, spinal cord, and muscle. Lancet. 1982 Sep 11;2(8298):597–600. doi: 10.1016/s0140-6736(82)90670-5. [DOI] [PubMed] [Google Scholar]
  8. Merton P. A., Morton H. B. Stimulation of the cerebral cortex in the intact human subject. Nature. 1980 May 22;285(5762):227–227. doi: 10.1038/285227a0. [DOI] [PubMed] [Google Scholar]
  9. Mills K. R., Murray N. M. Corticospinal tract conduction time in multiple sclerosis. Ann Neurol. 1985 Nov;18(5):601–605. doi: 10.1002/ana.410180514. [DOI] [PubMed] [Google Scholar]
  10. Radtke R. A., Erwin A., Erwin C. W. Abnormal sensory evoked potentials in amyotrophic lateral sclerosis. Neurology. 1986 Jun;36(6):796–801. doi: 10.1212/wnl.36.6.796. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES