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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1987 Jun;50(6):752–757. doi: 10.1136/jnnp.50.6.752

Dominantly inherited Alzheimer's disease: cerebral glucose metabolism.

R J Polinsky, H Noble, G Di Chiro, L E Nee, R G Feldman, R T Brown
PMCID: PMC1032083  PMID: 3497227

Abstract

Cerebral glucose metabolic rate (CMRGlu), measured by positron emission tomography, was bilaterally and symmetrically reduced in two patients with autosomal dominant Alzheimer's disease. Supramarginal gyri and temporal lobes were most severely affected. An isolated reduction of CMRGlu in the left supramarginal gyrus was observed in one asymptomatic at-risk subject.

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Selected References

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