Abstract
Two patients with clinically definite multiple sclerosis presented with acute hypothermia and on recovery were found to be chronically hypothermic. Thermoregulatory studies indicated a central, hypothalamic defect which is presumed to be due to a plaque of demyelination.
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Selected References
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- Apple D., Kreines K., Biehl J. P. The syndrome of inappropriate antidiuretic hormone secretion in multiple sclerosis. Arch Intern Med. 1978 Nov;138(11):1713–1714. [PubMed] [Google Scholar]
- Cohen I. J., Amir J., Gedaliah A., Rachmal A., Gorodischer R., Zaizov R. Thrombocytopenia of neonatal cold injury. J Pediatr. 1984 Apr;104(4):620–622. doi: 10.1016/s0022-3476(84)80565-x. [DOI] [PubMed] [Google Scholar]
- Fox R. H., Davies T. W., Marsh F. P., Urich H. Hypothermia in a young man with an anterior hypothalamic lesion. Lancet. 1970 Jul 25;2(7665):185–188. doi: 10.1016/s0140-6736(70)92538-9. [DOI] [PubMed] [Google Scholar]
- Kurtzke J. F. Neurologic impairment in multiple sclerosis and the disability status scale. Acta Neurol Scand. 1970;46(4):493–512. doi: 10.1111/j.1600-0404.1970.tb05808.x. [DOI] [PubMed] [Google Scholar]
- Ratcliffe P. J., Bell J. I., Collins K. J., Frackowiak R. S., Rudge P. Late onset post-traumatic hypothalamic hypothermia. J Neurol Neurosurg Psychiatry. 1983 Jan;46(1):72–74. doi: 10.1136/jnnp.46.1.72. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Symington G. R., Mackay I. R., Currie T. T. Improvement in multiple sclerosis during prolonged induced hypothermia. Neurology. 1977 Mar;27(3):302–303. doi: 10.1212/wnl.27.3.302. [DOI] [PubMed] [Google Scholar]
- VILLALOBOS T. J., ADELSON E., RILEY P. A., Jr, CROSBY W. H. A cause of the thrombocytopenia and leukopenia that occur in dogs during deep hypothermia. J Clin Invest. 1958 Jan;37(1):1–7. doi: 10.1172/JCI103576. [DOI] [PMC free article] [PubMed] [Google Scholar]
