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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1989 Apr;52(4):536–538. doi: 10.1136/jnnp.52.4.536

Peripheral neuropathy associated with mycosis fungoides.

M Comola 1, R Nemni 1, G Comi 1, M Corbo 1, G Taccagni 1, C Besana 1, N Canal 1
PMCID: PMC1032313  PMID: 2738598

Abstract

A 56 year old man with acute sensory-motor polyneuropathy associated with mycosis fungoides is described. EMG studies showed diffuse signs of muscle denervation. A skin biopsy specimen showed a lymphocyte infiltration in the dermis, composed of mycosis cells characterised by deep invaginations of the nuclear membrane, and small Pautrier's microabscesses in the epidermis. Sural nerve biopsy revealed endoneurial fibrosis, a decreased number of myelinated fibres and acute axonal degeneration.

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Selected References

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