Abstract
Elderly patients with major depression and normal controls completed the Sternberg short-term memory scanning procedure and WAIS Digit Symbol. Depressed patients demonstrated psychomotor slowing on both tasks, but normal response latency as a function of memory set size on the Sternberg procedure. While cognitive-behavioural slowing may be observed in both depressive illness and subcortical neurological disorders, a normal rate of processing information centrally appears to distinguish depression from certain of these disorders. Psychomotor slowing in the presence of normal information processing speed might be explained by a deficit in motivational state associated with depression.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Albert M. L., Feldman R. G., Willis A. L. The 'subcortical dementia' of progressive supranuclear palsy. J Neurol Neurosurg Psychiatry. 1974 Feb;37(2):121–130. doi: 10.1136/jnnp.37.2.121. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Caine E. D. Pseudodementia. Current concepts and future directions. Arch Gen Psychiatry. 1981 Dec;38(12):1359–1364. doi: 10.1001/archpsyc.1981.01780370061008. [DOI] [PubMed] [Google Scholar]
- Cohen R. M., Weingartner H., Smallberg S. A., Pickar D., Murphy D. L. Effort and cognition in depression. Arch Gen Psychiatry. 1982 May;39(5):593–597. doi: 10.1001/archpsyc.1982.04290050061012. [DOI] [PubMed] [Google Scholar]
- Cummings J. L., Benson D. F. Subcortical dementia. Review of an emerging concept. Arch Neurol. 1984 Aug;41(8):874–879. doi: 10.1001/archneur.1984.04050190080019. [DOI] [PubMed] [Google Scholar]
- Hamilton M. Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol. 1967 Dec;6(4):278–296. doi: 10.1111/j.2044-8260.1967.tb00530.x. [DOI] [PubMed] [Google Scholar]
- Hart R. P., Henry G. K., Kwentus J. A., Leshner R. T. Information processing speed of children with Friedreich's ataxia. Dev Med Child Neurol. 1986 Jun;28(3):310–313. doi: 10.1111/j.1469-8749.1986.tb03878.x. [DOI] [PubMed] [Google Scholar]
- Hart R. P., Kwentus J. A., Leshner R. T., Frazier R. Information processing speed in Friedreich's ataxia. Ann Neurol. 1985 Jun;17(6):612–614. doi: 10.1002/ana.410170615. [DOI] [PubMed] [Google Scholar]
- Henry G. M., Weingartner H., Murphy D. L. Influence of affective states and psychoactive drugs on verbal learning and memory. Am J Psychiatry. 1973 Sep;130(9):966–971. doi: 10.1176/ajp.130.9.966. [DOI] [PubMed] [Google Scholar]
- Huber S. J., Paulson G. W. The concept of subcortical dementia. Am J Psychiatry. 1985 Nov;142(11):1312–1317. doi: 10.1176/ajp.142.11.1312. [DOI] [PubMed] [Google Scholar]
- McAllister T. W. Overview: pseudodementia. Am J Psychiatry. 1983 May;140(5):528–533. doi: 10.1176/ajp.140.5.528. [DOI] [PubMed] [Google Scholar]
- Miller E., Lewis P. Recognition memory in elderly patients with depression and dementia: a signal detection analysis. J Abnorm Psychol. 1977 Feb;86(1):84–86. doi: 10.1037//0021-843x.86.1.84. [DOI] [PubMed] [Google Scholar]
- Reding M., Haycox J., Blass J. Depression in patients referred to a dementia clinic. A three-year prospective study. Arch Neurol. 1985 Sep;42(9):894–896. doi: 10.1001/archneur.1985.04060080080019. [DOI] [PubMed] [Google Scholar]
- Reus V. I., Silberman E., Post R. M., Weingartner H. d-Amphetamine: effects on memory in a depressed population. Biol Psychiatry. 1979 Apr;14(2):345–356. [PubMed] [Google Scholar]
- Weingartner H., Cohen R. M., Murphy D. L., Martello J., Gerdt C. Cognitive processes in depression. Arch Gen Psychiatry. 1981 Jan;38(1):42–47. doi: 10.1001/archpsyc.1981.01780260044004. [DOI] [PubMed] [Google Scholar]
- Whitehouse P. J. The concept of subcortical and cortical dementia: another look. Ann Neurol. 1986 Jan;19(1):1–6. doi: 10.1002/ana.410190102. [DOI] [PubMed] [Google Scholar]
- Wilson R. S., Kaszniak A. W., Klawans H. L., Garron D. C. High speed memory scanning in parkinsonism. Cortex. 1980 Mar;16(1):67–72. doi: 10.1016/s0010-9452(80)80022-0. [DOI] [PubMed] [Google Scholar]