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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1987 Nov;50(11):1536–1538. doi: 10.1136/jnnp.50.11.1536

Reterogasserian anhydrous glycerol injection therapy in trigeminal neuralgia: observations in 552 patients.

S S Saini 1
PMCID: PMC1032571  PMID: 3501000

Abstract

Five hundred and fifty two patients with trigeminal neuralgia were treated with reterogasserian anhydrous glycerol injections. Two hundred and twenty four patients (59.1%) at the end of two years and eight patients (8.1%) at the end of six years were free from pain after a single injection. There was recurrence of pain in 136 patients (27.7%) after one year and in an additional 155 patients (40.9%) after two years. The recurrence was seen earlier in patients who had either a neurolytic injection or had undergone surgical procedures, compared with those patients who had been treated with drugs. Complications of injection were few and not incapacitating. The technique was found to be safe, cheap and effective in treating trigeminal neuralgia, and is recommended for centres where there are financial constraints.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arias M. J. Percutaneous retrogasserian glycerol rhizotomy for trigeminal neuralgia. A prospective study of 100 cases. J Neurosurg. 1986 Jul;65(1):32–36. doi: 10.3171/jns.1986.65.1.0032. [DOI] [PubMed] [Google Scholar]
  2. Beck D. W., Olson J. J., Urig E. J. Percutaneous retrogasserian glycerol rhizotomy for treatment of trigeminal neuralgia. J Neurosurg. 1986 Jul;65(1):28–31. doi: 10.3171/jns.1986.65.1.0028. [DOI] [PubMed] [Google Scholar]
  3. Calvin W. H., Loeser J. D., Howe J. F. A neurophysiological theory for the pain mechanism of tic douloureux. Pain. 1977 Apr;3(2):147–154. doi: 10.1016/0304-3959(77)90078-1. [DOI] [PubMed] [Google Scholar]
  4. Jannetta P. J. Treatment of trigeminal neuralgia by suboccipital and transtentorial cranial operations. Clin Neurosurg. 1977;24:538–549. doi: 10.1093/neurosurgery/24.cn_suppl_1.538. [DOI] [PubMed] [Google Scholar]
  5. Loeser J. D., Calvin W. H., Howe J. F. Pathophysiology of trigeminal neuralgia. Clin Neurosurg. 1977;24:527–537. doi: 10.1093/neurosurgery/24.cn_suppl_1.527. [DOI] [PubMed] [Google Scholar]
  6. Lunsford L. D., Bennett M. H., Martinez A. J. Experimental trigeminal glycerol injection. Electrophysiologic and morphologic effects. Arch Neurol. 1985 Feb;42(2):146–149. doi: 10.1001/archneur.1985.04060020060016. [DOI] [PubMed] [Google Scholar]
  7. Lunsford L. D., Bennett M. H. Percutaneous retrogasserian glycerol rhizotomy for tic douloureux: Part 1. Technique and results in 112 patients. Neurosurgery. 1984 Apr;14(4):424–430. doi: 10.1227/00006123-198404000-00006. [DOI] [PubMed] [Google Scholar]
  8. Menzel J., Piotrowski W., Penzholz H. Long-term results of Gasserian ganglion electrocoagulation. J Neurosurg. 1975 Feb;42(2):140–143. doi: 10.3171/jns.1975.42.2.0140. [DOI] [PubMed] [Google Scholar]
  9. Nugent G. R., Berry B. Trigeminal neuralgia treated by differential percutaneous radiofrequency coagulation of the Gasserian ganglion. J Neurosurg. 1974 Apr;40(4):517–523. doi: 10.3171/jns.1974.40.4.0517. [DOI] [PubMed] [Google Scholar]
  10. Rao S. B., Dinakar I. Trigeminal neuralgia. Neurol India. 1970 Sep;18(3):181–184. [PubMed] [Google Scholar]
  11. Schürmann K., Butz M., Brock M. Temporal retrogasserian resection of trigeminal root versus controlled elective percutaneous electrocoagulation of the ganglion of gasser in the treatment of trigeminal neuralgia. Report on a series of 531 cases. Acta Neurochir (Wien) 1972;26(1):33–53. doi: 10.1007/BF01413531. [DOI] [PubMed] [Google Scholar]
  12. Sweet W. H., Poletti C. E., Macon J. B. Treatment of trigeminal neuralgia and other facial pains by retrogasserian injection of glycerol. Neurosurgery. 1981 Dec;9(6):647–653. doi: 10.1227/00006123-198112000-00006. [DOI] [PubMed] [Google Scholar]
  13. Sweet W. H., Wepsic J. G. Controlled thermocoagulation of trigeminal ganglion and rootlets for differential destruction of pain fibers. 1. Trigeminal neuralgia. J Neurosurg. 1974 Feb;40(2):143–156. doi: 10.3171/jns.1974.40.2.0143. [DOI] [PubMed] [Google Scholar]

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