Skip to main content
NCBI home page
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1987 Dec;50(12):1619–1624. doi: 10.1136/jnnp.50.12.1619

Oligodendroglioma occurring after radiation therapy for pituitary adenoma.

C I Huang 1, W H Chiou 1, D M Ho 1
PMCID: PMC1032603  PMID: 3325615

Abstract

A 38 year old male dentist developed an oligodendroglioma of the left medial temporal lobe and parasellar region 12 years after radiotherapy with 6600 rads of acromegaly. The 30 cases of radiation-induced gliomas reported in the English literature are reviewed and analysed. The criteria for defining radiation-induced tumours of the central nervous system are proposed as follows: the tumour has a long quiescent "latency period", a location in the previously irradiated field, a verified histological difference from a primary condition, and does not arise from a primary condition associated with a genetic syndrome such as neurofibromatosis or tuberous sclerosis. The reported case fulfilled these criteria but appears to be the only reported radiation-induced oligodendroglioma.

Full text

PDF
1619

Images in this article

1620Image
on p.1620
1620Image
on p.1620
1621Image
on p.1621

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALFORD T. C., KLOPP C. T. The surgical treatment of cancer of the floor of the mouth. Cancer. 1958 Jan-Feb;11(1):1–3. doi: 10.1002/1097-0142(195801/02)11:1<1::aid-cncr2820110102>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]
  2. BATZDORF U., MALAMUD N. THE PROBLEM OF MULTICENTRIC GLIOMAS. J Neurosurg. 1963 Feb;20:122–136. doi: 10.3171/jns.1963.20.2.0122. [DOI] [PubMed] [Google Scholar]
  3. Bachman D. S., Ostrow P. T. Fatal long-term sequela following radiation "cure" for ependymoma. Ann Neurol. 1978 Oct;4(4):319–321. doi: 10.1002/ana.410040406. [DOI] [PubMed] [Google Scholar]
  4. Barnes A. E., Liwnicz B. H., Schellhas H. F., Altshuler G., Aron B. S., Lippert W. A. Successful treatment of placental choriocarcinoma metastatic to brain followed by primary brain glioblastoma. Gynecol Oncol. 1982 Feb;13(1):108–114. doi: 10.1016/0090-8258(82)90015-4. [DOI] [PubMed] [Google Scholar]
  5. Castanera T. J., Jones D. C., Kimeldorf D. J., Rosen V. J. The influence of whole-body exposure to x-rays or neutrons on the life span distribution of tumors among male rats. Cancer Res. 1968 Feb;28(2):170–182. [PubMed] [Google Scholar]
  6. Chung C. K., Stryker J. A., Cruse R., Vannuci R., Towfighi J. Glioblastoma multiforme following prophylactic cranial irradiation and intrathecal methotrexate in a child with acute lymphocytic leukemia. Cancer. 1981 Jun 1;47(11):2563–2566. doi: 10.1002/1097-0142(19810601)47:11<2563::aid-cncr2820471108>3.0.co;2-o. [DOI] [PubMed] [Google Scholar]
  7. Clifton M. D., Amromin G. D., Perry M. C., Abadir R., Watts C., Levy N. Spinal cord glioma following irradiation for Hodgkin's disease. Cancer. 1980 Apr 15;45(8):2051–2055. doi: 10.1002/1097-0142(19800415)45:8<2051::aid-cncr2820450811>3.0.co;2-3. [DOI] [PubMed] [Google Scholar]
  8. Deen H. G., Jr, Laws E. R., Jr Multiple primary brain tumors of different cell types. Neurosurgery. 1981 Jan;8(1):20–25. doi: 10.1227/00006123-198101000-00005. [DOI] [PubMed] [Google Scholar]
  9. Gutjahr P., Dieterich E. Risiko zweiter maligner Neoplasien nach erfolgreicher Tumorbehandlung im Kindesalter. Dtsch Med Wochenschr. 1979 Jul 6;104(27):969–972. doi: 10.1055/s-0028-1129019. [DOI] [PubMed] [Google Scholar]
  10. Haselow R. E., Nesbit M., Dehner L. P., Khan F. M., McHugh R., Levitt S. H. Second neoplasms following megavoltage radiation in a pediatric population. Cancer. 1978 Sep;42(3):1185–1191. doi: 10.1002/1097-0142(197809)42:3<1185::aid-cncr2820420323>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]
  11. Haymaker W., Rubinstein L. J., Miquel J. Brain tumors in irradiated monkeys. Acta Neuropathol. 1972;20(4):267–277. doi: 10.1007/BF00691745. [DOI] [PubMed] [Google Scholar]
  12. Iacono R. P., Apuzzo M. L., Davis R. L., Tsai F. Y. Multiple meningiomas following radiation therapy for medulloblastoma. Case report. J Neurosurg. 1981 Aug;55(2):282–286. doi: 10.3171/jns.1981.55.2.0282. [DOI] [PubMed] [Google Scholar]
  13. Komaki S., Komaki R., Choi H., Correa-Paz F. Radiation- and drug-induced intracranial neoplasm with angiographic demonstration. Neurol Med Chir (Tokyo) 1977;17(1 Pt 1):55–62. doi: 10.2176/nmc.17pt1.55. [DOI] [PubMed] [Google Scholar]
  14. Liwnicz B. H., Berger T. S., Liwnicz R. G., Aron B. S. Radiation-associated gliomas: a report of four cases and analysis of postradiation tumors of the central nervous system. Neurosurgery. 1985 Sep;17(3):436–445. doi: 10.1227/00006123-198509000-00007. [DOI] [PubMed] [Google Scholar]
  15. Modan B., Baidatz D., Mart H., Steinitz R., Levin S. G. Radiation-induced head and neck tumours. Lancet. 1974 Feb 23;1(7852):277–279. doi: 10.1016/s0140-6736(74)92592-6. [DOI] [PubMed] [Google Scholar]
  16. NOETZLI M., MALAMUD N. Postirradiation fibrosarcoma of the brain. Cancer. 1962 May-Jun;15:617–622. doi: 10.1002/1097-0142(196205/06)15:3<617::aid-cncr2820150324>3.0.co;2-k. [DOI] [PubMed] [Google Scholar]
  17. Pearl G. S., Mirra S. S., Miles M. L. Glioblastoma multiforme occurring 13 years after treatment of a medulloblastoma. Neurosurgery. 1980 May;6(5):546–551. doi: 10.1227/00006123-198005000-00009. [DOI] [PubMed] [Google Scholar]
  18. Preissig S. H., Bohmfalk G. L., Reichel G. W., Smith M. T. Anaplastic astrocytoma following radiation for a glomus jugular tumor. Cancer. 1979 Jun;43(6):2243–2247. doi: 10.1002/1097-0142(197906)43:6<2243::aid-cncr2820430614>3.0.co;2-k. [DOI] [PubMed] [Google Scholar]
  19. Raffel C., Edwards M. S., Davis R. L., Ablin A. R. Postirradiation cerebellar glioma. Case report. J Neurosurg. 1985 Feb;62(2):300–303. doi: 10.3171/jns.1985.62.2.0300. [DOI] [PubMed] [Google Scholar]
  20. Robinson R. G. A second brain tumour and irradiation. J Neurol Neurosurg Psychiatry. 1978 Nov;41(11):1005–1012. doi: 10.1136/jnnp.41.11.1005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. SAENGER E. L., SILVERMAN F. N., STERLING T. D., TURNER M. E. Neoplasia following therapeutic irradiation for benign conditions in childhood. Radiology. 1960 Jun;74:889–904. doi: 10.1148/74.6.889. [DOI] [PubMed] [Google Scholar]
  22. Sanders J., Sale G. E., Ramberg R., Clift R., Buckner C. D., Thomas E. D. Glioblastoma multiforme in a patient with acute lymphoblastic leukemia who received a marrow transplant. Transplant Proc. 1982 Dec;14(4):770–774. [PubMed] [Google Scholar]
  23. Spector B. D., Perry G. S., 3rd, Kersey J. H. Genetically determined immunodeficiency diseases (GDID) and malignancy: report from the immunodeficiency--cancer registry. Clin Immunol Immunopathol. 1978 Sep;11(1):12–29. doi: 10.1016/0090-1229(78)90200-3. [DOI] [PubMed] [Google Scholar]
  24. Zochodne D. W., Cairncross J. G., Arce F. P., MacDonald J. C., Blume W. T., Girvin J. P., Kaufmann J. C. Astrocytoma following scalp radiotherapy in infancy. Can J Neurol Sci. 1984 Nov;11(4):475–478. doi: 10.1017/s0317167100046047. [DOI] [PubMed] [Google Scholar]
  25. Zuccarello M., Sawaya R., deCourten-Meyers G. Glioblastoma occurring after radiation therapy for meningioma: case report and review of literature. Neurosurgery. 1986 Jul;19(1):114–119. doi: 10.1227/00006123-198607000-00019. [DOI] [PubMed] [Google Scholar]
  26. vanAnkeren S. C., Wheeler K. T. Relationship between the repair of radiation-induced DNA damage and recovery from potentially lethal damage in 9L rat brain tumor cells. Cancer Res. 1984 Mar;44(3):1091–1097. [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES