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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1988 Mar;51(3):374–378. doi: 10.1136/jnnp.51.3.374

Adrenal cortex hormones in male epileptic patients before and during a 2-year phenytoin treatment.

Z Ostrowska 1, B Buntner 1, D Rościszewska 1, I Guz 1
PMCID: PMC1032863  PMID: 3129539

Abstract

Serum levels of progesterone, cortisol and phenytoin as well as the excretion of 17-OHCS were determined in 45 male epileptics before and during 24 months of the therapy. A significant decrease of the hormones was found in untreated patients. Phenytoin administration caused further decrease of cortisol and its metabolite 17-OHCS levels and a compensation of progesterone serum concentration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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