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. 1987 Jan;50(1):30–36. doi: 10.1136/jnnp.50.1.30

Tuberculous meningitis: role of CT in management and prognosis.

D P Kingsley, W A Hendrickse, B E Kendall, M Swash, V Singh
PMCID: PMC1033246  PMID: 3819753

Abstract

Serial computed tomographic scans were performed during the course of tuberculous meningitis in 25 patients aged 1-70 years. Hydrocephalus rarely occurred without other abnormalities. Marked ventricular enlargement was associated with extensive basal enhancement. Basal meningeal enhancement was not a good indicator of the clinical state although marked enhancement was a risk factor for the development of basal ganglia infarction. Infarcts were much more common in children than in adults and were sometimes asymptomatic. Radiological abnormalities sometimes developed during treatment and often did not resolve completely. Many patients had severe residual neurological problems.

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Selected References

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  1. Bateman D. E., Newman P. K., Foster J. B. A retrospective survey of proven cases of tuberculous meningitis in the Northern Region, 1970-1980. J R Coll Physicians Lond. 1983 Apr;17(2):106–110. [PMC free article] [PubMed] [Google Scholar]
  2. Bhargava S., Gupta A. K., Tandon P. N. Tuberculous meningitis--a CT study. Br J Radiol. 1982 Mar;55(651):189–196. doi: 10.1259/0007-1285-55-651-189. [DOI] [PubMed] [Google Scholar]
  3. Bullock M. R., Welchman J. M. Diagnostic and prognostic features of tuberculous meningitis on CT scanning. J Neurol Neurosurg Psychiatry. 1982 Dec;45(12):1098–1101. doi: 10.1136/jnnp.45.12.1098. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Cassleman E. S., Hasso A. N., Ashwal S., Schneider S. Computed tomography of tuberculous meningitis in infants and children. J Comput Assist Tomogr. 1980 Apr;4(2):211–216. doi: 10.1097/00004728-198004000-00016. [DOI] [PubMed] [Google Scholar]
  5. Chambers A. A., Lukin R. R., Tomsick T. A. Cranial and intracranial tuberculosis. Semin Roentgenol. 1979 Oct;14(4):319–324. doi: 10.1016/0037-198x(79)90028-2. [DOI] [PubMed] [Google Scholar]
  6. Coyle J. T. Chiasmatic arachnoiditis. A case report and review. Am J Ophthalmol. 1969 Aug;68(2):345–349. [PubMed] [Google Scholar]
  7. Dastur D. K., Lalitha V. S., Udani P. M., Parekh U. The brain and meninges in tuberculous meningitis-gross pathology in 100 cases and pathogenesis. Neurol India. 1970 Jun;18(2):86–100. [PubMed] [Google Scholar]
  8. Delage G., Dusseault M. Tuberculous meningitis in children: a retrospective study of 79 patients, with an analysis of prognostic factors. Can Med Assoc J. 1979 Feb 3;120(3):305–309. [PMC free article] [PubMed] [Google Scholar]
  9. Desai H. G., Anklesaria E. D. Ophthalmological aspects of tuberculous meningitis. J Indian Med Assoc. 1967 Nov 1;49(9):429–432. [PubMed] [Google Scholar]
  10. Forgan-Smith R., Newton D. Sarcoidosis, tuberculous meningitis and visual disturbance. Tubercle. 1974 Dec;55(4):309–312. doi: 10.1016/0041-3879(74)90040-3. [DOI] [PubMed] [Google Scholar]
  11. Idriss Z. H., Sinno A. A., Kronfol N. M. Tuberculous meningitis in childhood. Forty-three cases. Am J Dis Child. 1976 Apr;130(4):364–367. doi: 10.1001/archpedi.1976.02120050022004. [DOI] [PubMed] [Google Scholar]
  12. Kocen R. S. Meningitis. Tuberculous meningitis. Br J Hosp Med. 1977 Nov;18(5):436, 440-1, 443-4 passim. [PubMed] [Google Scholar]
  13. LEVINSON A., LUHAN J. A., MAVRELIS W. P., HERZON H. The effect of streptomycin on tuberculous meningitis. J Neuropathol Exp Neurol. 1950 Oct;9(4):406–419. doi: 10.1097/00005072-195010000-00006. [DOI] [PubMed] [Google Scholar]
  14. LORBER J. Studies of the cerebrospinal fluid circulation in tuberculous meningitis in children. Part II. A review of 100 pneumoencephalograms. Arch Dis Child. 1951 Feb;26(125):28–44. doi: 10.1136/adc.26.125.28. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Lebas J., Malkin J. E., Coquin Y., Modai J. Cerebral tuberculomas developing during treatment of tuberculous meningitis. Lancet. 1980 Jul 12;2(8185):84–84. [PubMed] [Google Scholar]
  16. Lees A. J., MacLeod A. F., Marshall J. Cerebral tuberculomas developing during treatment of tuberculous meningitis. Lancet. 1980 Jun 7;1(8180):1208–1211. doi: 10.1016/s0140-6736(80)91676-1. [DOI] [PubMed] [Google Scholar]
  17. Murray H. W., Brandstetter R. D., Lavyne M. H. Ventriculoatrial shunting for hydrocephalus complicating tuberculous meningitis. Am J Med. 1981 Apr;70(4):895–898. doi: 10.1016/0002-9343(81)90551-9. [DOI] [PubMed] [Google Scholar]
  18. Newman P. K., Cumming W. J., Foster J. B. Hydrocephalus and tuberculous meningitis in adults. J Neurol Neurosurg Psychiatry. 1980 Feb;43(2):188–190. doi: 10.1136/jnnp.43.2.188. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. O'Toole R. D., Thornton G. F., Mukherjee M. K., Nath R. L. Dexamethasone in tuberculous meningitis. Relationship of cerebrospinal fluid effects to therapeutic efficacy. Ann Intern Med. 1969 Jan;70(1):39–48. doi: 10.7326/0003-4819-70-1-39. [DOI] [PubMed] [Google Scholar]
  20. Poltera A. A. Thrombogenic intracranial vasculitis in tuberculous meningitis. A 20 year "post mortem" survey. Acta Neurol Belg. 1977 Jan-Feb;77(1):12–24. [PubMed] [Google Scholar]
  21. Poltera A. A. Vascular lesions in intracranial tuberculosis. Pathol Microbiol (Basel) 1975;43(2-O):192–194. doi: 10.1159/000162819. [DOI] [PubMed] [Google Scholar]
  22. Price H. I., Danziger A. Computed tomography in cranial tuberculosis. AJR Am J Roentgenol. 1978 Apr;130(4):769–771. doi: 10.2214/ajr.130.4.769. [DOI] [PubMed] [Google Scholar]
  23. Ramachandran R. S., Ramanathan K., Indra G. Tuberculous meningitis. A review of 288 cases in children. Indian J Pediatr. 1970 Mar;37(266):85–88. doi: 10.1007/BF02819806. [DOI] [PubMed] [Google Scholar]
  24. Rovira M., Romero F., Torrent O., Ibarra B. Study of tuberculous meningitis by CT. Neuroradiology. 1980 Apr;19(3):137–141. doi: 10.1007/BF00342388. [DOI] [PubMed] [Google Scholar]
  25. SMITH H. V. TUBERCULOUS MENINGITIS. Int J Neurol. 1964;4:134–157. [PubMed] [Google Scholar]
  26. Scott R. M., Sonntag V. K., Wilcox L. M., Adelman L. S., Rockel T. H. Visual loss from optochiasmatic arachnoiditis after tuberculous meningitis. Case report. J Neurosurg. 1977 Apr;46(4):524–526. doi: 10.3171/jns.1977.46.4.0524. [DOI] [PubMed] [Google Scholar]
  27. Swart S., Briggs R. S., Millac P. A. Tuberculous meningitis in Asian patients. Lancet. 1981 Jul 4;2(8236):15–16. doi: 10.1016/s0140-6736(81)90253-1. [DOI] [PubMed] [Google Scholar]
  28. Thomas M. D., Chopra J. S., Walia B. N. Tuberculous meningitis (T.B.M.)(a clinical study of 232 cases). J Assoc Physicians India. 1977 Sep;25(9):633–639. [PubMed] [Google Scholar]
  29. Traub M., Colchester A. C., Kingsley D. P., Swash M. Tuberculosis of the central nervous system. Q J Med. 1984 Winter;53(209):81–100. [PubMed] [Google Scholar]
  30. Udani P. M., Parekh U. C., Dastur D. K. Neurological and related syndromes in CNS tuberculosis. Clinical features and pathogenesis. J Neurol Sci. 1971 Nov;14(3):341–357. doi: 10.1016/0022-510x(71)90222-x. [DOI] [PubMed] [Google Scholar]

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