Fig. 7.

Single-cell RNA sequencing revealed the changes of cell death patterns in various immune cells in sepsis. A Expression difference of the key molecules of five cell death signaling (necroptosis, pyroptosis, apoptosis, autophagy, and ferroptosis) in the four immune cells in sepsis at the early stage. B Expression changes of the biomarkers related to the five cell death signaling in immune cells (p < 0.05). C Comparison of the significant degree of functional changes in different cell death pathways of the four immune cells in sepsis at the early stage. Bubble plots were drawn according to the percentage of significant DEGs in the related GO term.