Abstract
The authors have requested that this preprint be removed from Research Square.
Full Text
The Full Text of this preprint is available as a PDF (2.5 MB). The Web version will be available soon.
[Preprint]. 2023 Jun 30:rs.3.rs-3069713. [Version 1] doi: 10.21203/rs.3.rs-3069713/v1
[WITHDRAWN] Activation of transsulfuration pathway to maintain cysteine is a thermogenic checkpoint for the conservation of energy
Aileen H Lee
1,2,3, Yuki Sugiura
4, Yun-Hee Youm
1,2,3, Tamara Dlugos
1,2,3, Rae Maeda
4, Daniel Coman
5,6, Olga Spadaro
1,2,3, Sviatoslav Sidorov
1,2,3, Irina Shchukina
7, Sairam Andhey
7, Steven R Smith
8, Eric Ravussin
9, Fahmeed Hyder
5,6, Maxim N Artyomov
7, Vishwa Deep Dixit
1,2,3,10
Aileen H Lee
1Department of Pathology
2Department of Comparative Medicine
3Department of Immunobiology, Yale School of Medicine, New
Haven, CT 06520, USA.
Find articles by Aileen H Lee
Yun-Hee Youm
1Department of Pathology
2Department of Comparative Medicine
3Department of Immunobiology, Yale School of Medicine, New
Haven, CT 06520, USA.
Find articles by Yun-Hee Youm
Tamara Dlugos
1Department of Pathology
2Department of Comparative Medicine
3Department of Immunobiology, Yale School of Medicine, New
Haven, CT 06520, USA.
Find articles by Tamara Dlugos
Daniel Coman
5Department of Radiology and Biomedical Imaging
6Department of Biomedical Engineering, School of Engineering
and Applied Science, Yale University.
Find articles by Daniel Coman
Olga Spadaro
1Department of Pathology
2Department of Comparative Medicine
3Department of Immunobiology, Yale School of Medicine, New
Haven, CT 06520, USA.
Find articles by Olga Spadaro
Sviatoslav Sidorov
1Department of Pathology
2Department of Comparative Medicine
3Department of Immunobiology, Yale School of Medicine, New
Haven, CT 06520, USA.
Find articles by Sviatoslav Sidorov
Irina Shchukina
7Department of Pathology and Immunology Washington
University School of Medicine, St. Louis, MO 63110, USA.
Find articles by Irina Shchukina
Sairam Andhey
7Department of Pathology and Immunology Washington
University School of Medicine, St. Louis, MO 63110, USA.
Find articles by Sairam Andhey
Steven R Smith
8Translational Research Institute for Metabolism and
Diabetes, AdventHealth, Orlando, FL, USA.
Find articles by Steven R Smith
Eric Ravussin
9Pennington Biomedical Research Center, Baton Rouge, LA,
USA.
Find articles by Eric Ravussin
Fahmeed Hyder
5Department of Radiology and Biomedical Imaging
6Department of Biomedical Engineering, School of Engineering
and Applied Science, Yale University.
Find articles by Fahmeed Hyder
Maxim N Artyomov
7Department of Pathology and Immunology Washington
University School of Medicine, St. Louis, MO 63110, USA.
Find articles by Maxim N Artyomov
Vishwa Deep Dixit
1Department of Pathology
2Department of Comparative Medicine
3Department of Immunobiology, Yale School of Medicine, New
Haven, CT 06520, USA.
10Yale Center for Research on Aging, Yale School of
Medicine, New Haven, CT 06520, USA
Find articles by Vishwa Deep Dixit
1Department of Pathology
2Department of Comparative Medicine
3Department of Immunobiology, Yale School of Medicine, New
Haven, CT 06520, USA.
4University of Kyoto, Japan
5Department of Radiology and Biomedical Imaging
6Department of Biomedical Engineering, School of Engineering
and Applied Science, Yale University.
7Department of Pathology and Immunology Washington
University School of Medicine, St. Louis, MO 63110, USA.
8Translational Research Institute for Metabolism and
Diabetes, AdventHealth, Orlando, FL, USA.
9Pennington Biomedical Research Center, Baton Rouge, LA,
USA.
10Yale Center for Research on Aging, Yale School of
Medicine, New Haven, CT 06520, USA
✉
Lead Contact: Vishwa Deep Dixit, Yale School of Medicine, 310 Cedar St, New Haven CT 06520, Vishwa.Dixit@yale.edu, Phone: 203-785-2525, Fax: 203-785-7499
This work is licensed under a Creative Commons Attribution 4.0 International License, which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.
PMCID: PMC10350108 PMID: 37461682
The complete version history of this preprint is available at Research Square.