Abstract
Results are presented of a cohort study on the incidence of cancers and crude death rates in ferrochromium and ferrosilicon workers. The whole cohort was observed from 1 January 1953 to 31 December 1985. Two sets of results are presented; one restricted to workers first employed before 1960 and one to workers first employed before 1965. The latter cohort consists of 1235 workers. The total mortality in the whole cohort was low (SMR = 81) as was the overall incidence of cancers (SIR = 84). There was an overall deficit of deaths and cases of cancer in the ferrosilicon group. An excess of lung cancer (SIR = 154) and cancer of the prostate (SIR = 151) was observed in the ferrochromium workers employed before 1965. Cancer of the kidney was also in excess (SIR = 273) in the ferrochromium group, with a mean "latency time" of 39 years. Two cases of malignant melanomas had occurred versus 0.19 expected in a small subgroup of workers in electrical shops and an electric power station.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Axelsson G., Rylander R., Schmidt A. Mortality and incidence of tumours among ferrochromium workers. Br J Ind Med. 1980 May;37(2):121–127. doi: 10.1136/oem.37.2.121. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Heldaas S. S., Langård S. L., Andersen A. Incidence of cancer among vinyl chloride and polyvinyl chloride workers. Br J Ind Med. 1984 Feb;41(1):25–30. doi: 10.1136/oem.41.1.25. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kjuus H., Andersen A., Langård S. Incidence of cancer among workers producing calcium carbide. Br J Ind Med. 1986 Apr;43(4):237–242. doi: 10.1136/oem.43.4.237. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kjuus H., Lislerud A., Lyngdal P. T., Omland H., Stave O., Langård S. Cancer and polluted work places: a case-control study. Int Arch Occup Environ Health. 1982 Feb;49(3-4):281–292. doi: 10.1007/BF00377937. [DOI] [PubMed] [Google Scholar]
- O'Berg M. T., Burke C. A., Chen J. L., Walrath J., Pell S., Gallie C. R. Cancer incidence and mortality in the Du Pont Company: an update. J Occup Med. 1987 Mar;29(3):245–252. [PubMed] [Google Scholar]
- Purchase I. F. Procedures for screening chemicals for carcinogenicity. Br J Ind Med. 1980 Feb;37(1):1–10. doi: 10.1136/oem.37.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Storetvedt Heldaas S., Andersen A. A., Langård S. Incidence of cancer among vinyl chloride and polyvinyl chloride workers: further evidence for an association with malignant melanoma. Br J Ind Med. 1987 Apr;44(4):278–280. doi: 10.1136/oem.44.4.278. [DOI] [PMC free article] [PubMed] [Google Scholar]
- White P. C., New M. I., Dupont B. Cloning and expression of cDNA encoding a bovine adrenal cytochrome P-450 specific for steroid 21-hydroxylation. Proc Natl Acad Sci U S A. 1984 Apr;81(7):1986–1990. doi: 10.1073/pnas.81.7.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]