Abstract
A respiratory sample survey of 609 shipyard workers was conducted in 1979: the men were reassessed an average of 7.2 years later. The 53 deaths between the surveys were related to age, level of lung function and smoking but not to trade as a welder or caulker/burner. Of the survivors, 488 (88%) were seen, including 425 men who had retired or been made redundant. Redundancy was related to age, smoking, and respiratory symptoms; the average reduction in duration of employment per symptom was 0.44 years. Changes in respiratory symptoms included onset of chronic bronchitis and wheeze on most days (numbers respectively 77 and 109) and increased breathlessness on exertion (n = 89); significant related factors included smoking, previous metal fume fever or pneumonia, and, for breathlessness, trade as a welder or caulker/burner. Electrocardiographic evidence for myocardial ischaemia was also associated with increased breathlessness. The annual declines in FEV1 and other spirometric indices were related to age, to being a smoker at the time of the initial survey, and to trade as a welder or caulker/burner compared with trades that did not involve welding or burning. There was significant interaction between these effects. In a subsample of 124 redundant workers there was also significant interaction between the effects of fumes and atopy (skin test positive to common antigens) or a raised serum IgE concentration. It was concluded that welding fumes interacted with smoking and an atopic constitution to cause respiratory impairment. The results related mainly to exposures in the past and were not necessarily relevant for present day conditions in the industry.
Full text
PDF







Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Berry G. Longitudinal observations. Their usefulness and limitations with special reference to the forced expiratory volume. Bull Physiopathol Respir (Nancy) 1974 Sep-Oct;10(5):643–656. [PubMed] [Google Scholar]
- Brisson C., Loomis D., Pearce N. Is social class standardisation appropriate in occupational studies? J Epidemiol Community Health. 1987 Dec;41(4):290–294. doi: 10.1136/jech.41.4.290. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Burrows B., Lebowitz M. D., Barbee R. A. Respiratory disorders and allergy skin-test reactions. Ann Intern Med. 1976 Feb;84(2):134–139. doi: 10.7326/0003-4819-84-2-134. [DOI] [PubMed] [Google Scholar]
- Burrows B., Lebowitz M. D., Camilli A. E., Knudson R. J. Longitudinal changes in forced expiratory volume in one second in adults. Methodologic considerations and findings in healthy nonsmokers. Am Rev Respir Dis. 1986 Jun;133(6):974–980. doi: 10.1164/arrd.1986.133.6.974. [DOI] [PubMed] [Google Scholar]
- Cotes J. E., Feinmann E. L., Male V. J., Rennie F. S., Wickham C. A. Respiratory symptoms and impairment in shipyard welders and caulker/burners. Br J Ind Med. 1989 May;46(5):292–301. doi: 10.1136/oem.46.5.292. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cotes J. E. Occupational health today and tomorrow: a view from two shipyards. The Milroy lecture 1988. J R Coll Physicians Lond. 1988 Oct;22(4):232–236. [PMC free article] [PubMed] [Google Scholar]
- Kauffmann F., Drouet D., Lellouch J., Brille D. Twelve years spirometric changes among Paris area workers. Int J Epidemiol. 1979 Sep;8(3):201–212. doi: 10.1093/ije/8.3.201. [DOI] [PubMed] [Google Scholar]
- King B., Cotes J. E. Relation of lung function and exercise capacity to mood and attitudes to health. Thorax. 1989 May;44(5):402–409. doi: 10.1136/thx.44.5.402. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Miller M. R., Pincock A. C. Predicted values: how should we use them? Thorax. 1988 Apr;43(4):265–267. doi: 10.1136/thx.43.4.265. [DOI] [PMC free article] [PubMed] [Google Scholar]
- OLDHAM P. D. A note on the analysis of repeated measurements of the same subjects. J Chronic Dis. 1962 Oct;15:969–977. doi: 10.1016/0021-9681(62)90116-9. [DOI] [PubMed] [Google Scholar]
- Oldham P. D. Decline of FEV1. Thorax. 1987 Mar;42(3):161–164. doi: 10.1136/thx.42.3.161. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Taylor R. G., Joyce H., Gross E., Holland F., Pride N. B. Bronchial reactivity to inhaled histamine and annual rate of decline in FEV1 in male smokers and ex-smokers. Thorax. 1985 Jan;40(1):9–16. doi: 10.1136/thx.40.1.9. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wilhelmsen L., Wedel H., Tibblin G. Multivariate analysis of risk factors for coronary heart disease. Circulation. 1973 Nov;48(5):950–958. doi: 10.1161/01.cir.48.5.950. [DOI] [PubMed] [Google Scholar]