Abstract
A mortality study, concentrating on cardiovascular mortality, was undertaken among Finnish sulphite mill workers exposed to sulphur dioxide and sulphate mill workers exposed to hydrogen sulphide and organic sulphides. They had been employed continuously for at least one year between 1945 and 1961. National death rates were used for comparison and mortality was followed up until 31 December 1981. Among the cohort exposed to sulphur dioxide (2268 person-years), an excess of cardiovascular deaths was noticed among the men (24 obs, 19.4 exp, SMR 123) due to an excess of coronary deaths (18 obs, 12.4 exp, SMR 145). The cardiovascular mortality was not affected by the duration of occupational exposure or follow up period in this cohort. Among the men exposed to hydrogen sulphide and organic sulphides (4179 person-years), there was also an excess of cardiovascular deaths (37 obs, 24.7 exp, SMR 150) due to an excess of coronary deaths (25 obs, 16.7 exp, SMR 150). These excesses increased with longer follow up period. As common risk factors of coronary heart disease could not explain the findings in the sulphate mill cohort, they may be associated with exposure to hydrogen sulphide and organic sulphides.
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- Ferris B. G., Jr, Puleo S., Chen H. Y. Mortality and morbidity in a pulp and a paper mill in the United States: a ten-year follow-up. Br J Ind Med. 1979 May;36(2):127–134. doi: 10.1136/oem.36.2.127. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jäppinen P. A mortality study of Finnish pulp and paper workers. Br J Ind Med. 1987 Sep;44(9):580–587. [PMC free article] [PubMed] [Google Scholar]
- Jäppinen P., Tola S. Smoking among Finnish pulp and paper workers--evaluation of its confounding effect on lung cancer and coronary heart disease rates. Scand J Work Environ Health. 1986 Dec;12(6):619–626. doi: 10.5271/sjweh.2093. [DOI] [PubMed] [Google Scholar]
- KARVONEN M., ORMA E., KEYS A., FIDANZA F., BROZEK J. Cigarette smoking, serum-cholesterol, blood-pressure, and body fatness; observations in Finland. Lancet. 1959 Mar 7;1(7071):492–494. doi: 10.1016/s0140-6736(59)91022-0. [DOI] [PubMed] [Google Scholar]
- Kangas J., Jäppinen P., Savolainen H. Exposure to hydrogen sulfide, mercaptans and sulfur dioxide in pulp industry. Am Ind Hyg Assoc J. 1984 Dec;45(12):787–790. doi: 10.1080/15298668491400647. [DOI] [PubMed] [Google Scholar]
- Milham S., Jr, Demers R. Y. Mortality among pulp and paper workers. J Occup Med. 1984 Nov;26(11):844–846. doi: 10.1097/00043764-198411000-00016. [DOI] [PubMed] [Google Scholar]
- Poukkula A., Huhti E., Mäkaräinen M. Chronic respiratory disease among workers in a pulp mill: a ten-year follow-up study. Chest. 1982 Mar;81(3):285–289. doi: 10.1378/chest.81.3.285. [DOI] [PubMed] [Google Scholar]
- Robinson C. F., Waxweiler R. J., Fowler D. P. Mortality among production workers in pulp and paper mills. Scand J Work Environ Health. 1986 Dec;12(6):552–560. doi: 10.5271/sjweh.2101. [DOI] [PubMed] [Google Scholar]
- Salonen J. T., Puska P., Kottke T. E., Tuomilehto J., Nissinen A. Decline in mortality from coronary heart disease in Finland from 1969 to 1979. Br Med J (Clin Res Ed) 1983 Jun 11;286(6381):1857–1860. doi: 10.1136/bmj.286.6381.1857. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wilms J., Lub J., Wever R. Reactions of mercaptans with cytochrome c oxidase and cytochrome c. Biochim Biophys Acta. 1980 Feb 8;589(2):324–335. doi: 10.1016/0005-2728(80)90048-1. [DOI] [PubMed] [Google Scholar]