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. 1990 May;47(5):317–324. doi: 10.1136/oem.47.5.317

Occupation and malignant melanoma: a study based on cancer registration data in England and Wales and in Sweden.

D Vågerö 1, A J Swerdlow 1, V Beral 1
PMCID: PMC1035167  PMID: 2357453

Abstract

An analysis of the incidence of malignant melanoma according to occupation is presented using data from two national cancer registries. The data relate to 3991 cases of cutaneous malignant melanoma, 662 cases of ocular melanoma, and 179 cases of noncutaneous, non-ocular melanoma in subjects aged 15-64 in England and Wales diagnosed from 1971 to 1978 and to 5003 cases of cutaneous malignant melanoma diagnosed from 1961 to 1979 in Sweden in subjects born between 1896 and 1940. Professional workers of both sexes in both countries experienced an excess incidence of cutaneous malignant melanoma. An excess of ocular melanoma and of non-cutaneous, non-ocular melanoma also existed for this group in England and Wales. Pharmacists, medical doctors, and dentists had a high incidence of cutaneous melanoma in both countries and were represented three times when listing the top 20 occupations in both countries and both genders. Combining the data from cutaneous malignant melanoma over both sexes and both registries the occupations with the highest incidence ratios (expressed as a percentage) were: airline pilots, incidence ratio (IR) = 273, (95% confidence limits 118-538); finance and insurance brokers IR = 245 (140-398); professional accountants IR = 208 (134-307); dentists IR = 207 (133-309); inspectors and supervisors in transport IR = 206 (133-304); pharmacists IR = 198 (115-318); professionals not elsewhere classified IR = 196 (155-243); judges IR = 196 (126-289); doctors IR = 188 (140-248); university teachers IR = 188 (110-302); and chemists IR = 188 (111-296). No particular exposure in the workplace seemed to link these groups and only a few worked in high technology environments. Many of the highest risk groups have in common a high level of education. In England and Wales and in Sweden this might correlate particularly with foreign travel abroad was more unusual than it is now, but evidence on present and past exposure to sun by occupation is needed to clarify the reasons for the association.

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Selected References

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  1. Acquavella J. F., Tietjen G. L., Wilkinson G. S., Key C. R., Voelz G. L. Malignant melanoma incidence at the Los Alamos National Laboratory. Lancet. 1982 Apr 17;1(8277):883–884. doi: 10.1016/s0140-6736(82)92153-5. [DOI] [PubMed] [Google Scholar]
  2. Austin D. F., Reynolds P. J., Snyder M. A., Biggs M. W., Stubbs H. A. Malignant melanoma among employees of Lawrence Livermore National Laboratory. Lancet. 1981 Oct 3;2(8249):712–716. doi: 10.1016/s0140-6736(81)91047-3. [DOI] [PubMed] [Google Scholar]
  3. Bahn A. K., Rosenwaike I., Hermann N., Grover P., Stellman J., O'Leary K. Letter: Melanoma after exposure to PCB's. N Engl J Med. 1976 Aug 19;295(8):450–450. doi: 10.1056/NEJM197608192950820. [DOI] [PubMed] [Google Scholar]
  4. Beral V., Evans S., Shaw H., Milton G. Malignant melanoma and exposure to fluorescent lighting at work. Lancet. 1982 Aug 7;2(8293):290–293. doi: 10.1016/s0140-6736(82)90270-7. [DOI] [PubMed] [Google Scholar]
  5. Beral V., Robinson N. The relationship of malignant melanoma, basal and squamous skin cancers to indoor and outdoor work. Br J Cancer. 1981 Dec;44(6):886–891. doi: 10.1038/bjc.1981.288. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Blair A., Hayes H. M., Jr Cancer and other causes of death among U.S. veterinarians, 1966-1977. Int J Cancer. 1980 Feb 15;25(2):181–185. doi: 10.1002/ijc.2910250203. [DOI] [PubMed] [Google Scholar]
  7. Chase K. H., Wong O., Thomas D., Berney B. W., Simon R. K. Clinical and metabolic abnormalities associated with occupational exposure to polychlorinated biphenyls (PCBs). J Occup Med. 1982 Feb;24(2):109–114. [PubMed] [Google Scholar]
  8. Gallagher R. P., Elwood J. M., Threlfall W. J., Band P. R., Spinelli J. J. Occupation and risk of cutaneous melanoma. Am J Ind Med. 1986;9(3):289–294. doi: 10.1002/ajim.4700090312. [DOI] [PubMed] [Google Scholar]
  9. Heldaas S. S., Langård S. L., Andersen A. Incidence of cancer among vinyl chloride and polyvinyl chloride workers. Br J Ind Med. 1984 Feb;41(1):25–30. doi: 10.1136/oem.41.1.25. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hilt B., Langård S., Andersen A., Rosenberg J. Asbestos exposure, smoking habits, and cancer incidence among production and maintenance workers in an electrochemical plant. Am J Ind Med. 1985;8(6):565–577. doi: 10.1002/ajim.4700080608. [DOI] [PubMed] [Google Scholar]
  11. Lee J. A., Strickland D. Malignant melanoma: social status and outdoor work. Br J Cancer. 1980 May;41(5):757–763. doi: 10.1038/bjc.1980.138. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Olin R., Vågerö D., Ahlbom A. Mortality experience of electrical engineers. Br J Ind Med. 1985 Mar;42(3):211–212. doi: 10.1136/oem.42.3.211. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Roman E., Beral V., Inskip H., McDowall M., Adelstein A. A comparison of standardized and proportional mortality ratios. Stat Med. 1984 Jan-Mar;3(1):7–14. doi: 10.1002/sim.4780030103. [DOI] [PubMed] [Google Scholar]
  14. Rushton L., Alderson M. R. An epidemiological survey of eight oil refineries in Britain. Br J Ind Med. 1981 Aug;38(3):225–234. doi: 10.1136/oem.38.3.225. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Sorahan T., Waterhouse J. A., McKiernan M. J., Aston R. H. Cancer incidence and cancer mortality in a cohort of semiconductor workers. Br J Ind Med. 1985 Aug;42(8):546–550. doi: 10.1136/oem.42.8.546. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Swerdlow A. J. Epidemiology of eye cancer in adults in England and Wales, 1962-1977. Am J Epidemiol. 1983 Aug;118(2):294–300. doi: 10.1093/oxfordjournals.aje.a113636. [DOI] [PubMed] [Google Scholar]
  17. Thomas T. L., Decoufle P. Mortality among workers employed in the pharmaceutical industry: a preliminary investigation. J Occup Med. 1979 Sep;21(9):619–623. [PubMed] [Google Scholar]
  18. Thomas T. L., Decoufle P., Moure-Eraso R. Mortality among workers employed in petroleum refining and petrochemical plants. J Occup Med. 1980 Feb;22(2):97–103. doi: 10.1097/00043764-198002000-00007. [DOI] [PubMed] [Google Scholar]
  19. Urabe H., Asahi M. Past and current dermatological status of yusho patients. Environ Health Perspect. 1985 Feb;59:11–15. doi: 10.1289/ehp.59-1568099. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Vågero D., Ringbäck G., Kiviranta H. Melanoma and other tumors of the skin among office, other indoor and outdoor workers in Sweden 1961-1979. Br J Cancer. 1986 Apr;53(4):507–512. doi: 10.1038/bjc.1986.80. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Vågerö D., Ahlbom A., Olin R., Sahlsten S. Cancer morbidity among workers in the telecommunications industry. Br J Ind Med. 1985 Mar;42(3):191–195. doi: 10.1136/oem.42.3.191. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Wright W. E., Peters J. M., Mack T. M. Organic chemicals and malignant melanoma. Am J Ind Med. 1983;4(4):577–581. doi: 10.1002/ajim.4700040411. [DOI] [PubMed] [Google Scholar]

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