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. 1990 Sep;47(9):596–601. doi: 10.1136/oem.47.9.596

Effects of methyl isocyanate on rat brain cells in culture.

D Anderson 1, S Goyle 1, B J Phillips 1, A Tee 1, L Beech 1, W H Butler 1
PMCID: PMC1035244  PMID: 2207030

Abstract

Since the disaster in Bhopal, India, people exposed to methyl isocyanate (MIC) have complained of various disorders including neuromuscular dysfunction. In an attempt to get information about such dysfunction we have previously shown that MIC can affect muscle cells in culture. The present communication reports investigations into the effect of MIC on brain cells in culture. MIC was toxic to brain cells and the response was dose related. The observations were supported by light and electron microscopy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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