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British Journal of Industrial Medicine logoLink to British Journal of Industrial Medicine
. 1991 Feb;48(2):106–109. doi: 10.1136/oem.48.2.106

Blood and urine concentrations of aluminium among workers exposed to aluminium flake powders.

K G Ljunggren 1, V Lidums 1, B Sjögren 1
PMCID: PMC1035329  PMID: 1998604

Abstract

In a group of workers exposed to aluminium flake powders, blood and urine concentrations of aluminium were assessed before and after vacation. Another group was investigated after retirement. Workers currently exposed to aluminium flake powders had urinary concentrations of the metal 80-90 times higher than those in occupationally non-exposed referents. The calculated half life for concentrations of aluminium in urine was five to six weeks based on four to five weeks of non-exposure. Among the retired workers the half lives varied from less than one up to eight years and were related to the number of years since retirement. These results indicate that aluminium is retained and stored in several compartments of the body and eliminated from these compartments at different rates.

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Selected References

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  1. Alfrey A. C., LeGendre G. R., Kaehny W. D. The dialysis encephalopathy syndrome. Possible aluminum intoxication. N Engl J Med. 1976 Jan 22;294(4):184–188. doi: 10.1056/NEJM197601222940402. [DOI] [PubMed] [Google Scholar]
  2. Altmann P., Dhanesha U., Hamon C., Cunningham J., Blair J., Marsh F. Disturbance of cerebral function by aluminium in haemodialysis patients without overt aluminium toxicity. Lancet. 1989 Jul 1;2(8653):7–12. doi: 10.1016/s0140-6736(89)90254-7. [DOI] [PubMed] [Google Scholar]
  3. Frech W., Cedergren A., Cederberg C., Vessman J. Evaluation of some critical factors affecting determination of aluminum in blood, plasma, or serum by electrothermal atomic absorption spectroscopy. Clin Chem. 1982 Nov;28(11):2259–2263. [PubMed] [Google Scholar]
  4. MCLAUGHLIN A. I., KAZANTZIS G., KING E., TEARED, PORTER R. J., OWEN R. Pulmonary fibrosis and encephalopathy associated with the inhalation of aluminium dust. Br J Ind Med. 1962 Oct;19:253–263. doi: 10.1136/oem.19.4.253. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. McLachlan D. R., Lukiw W. J., Kruck T. P. New evidence for an active role of aluminum in Alzheimer's disease. Can J Neurol Sci. 1989 Nov;16(4 Suppl):490–497. doi: 10.1017/s0317167100029826. [DOI] [PubMed] [Google Scholar]
  6. Schreeder M. T., Favero M. S., Hughes J. R., Petersen N. J., Bennett P. H., Maynard J. E. Dialysis encephalopathy and aluminum exposure: an epidemiologic analysis. J Chronic Dis. 1983;36(8):581–593. doi: 10.1016/0021-9681(83)90146-7. [DOI] [PubMed] [Google Scholar]
  7. Sjögren B., Elinder C. G., Lidums V., Chang G. Uptake and urinary excretion of aluminum among welders. Int Arch Occup Environ Health. 1988;60(2):77–79. doi: 10.1007/BF00381484. [DOI] [PubMed] [Google Scholar]
  8. Sjögren B., Gustavsson P., Hogstedt C. Neuropsychiatric symptoms among welders exposed to neurotoxic metals. Br J Ind Med. 1990 Oct;47(10):704–707. doi: 10.1136/oem.47.10.704. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Sjögren B., Lidums V., Håkansson M., Hedström L. Exposure and urinary excretion of aluminum during welding. Scand J Work Environ Health. 1985 Feb;11(1):39–43. doi: 10.5271/sjweh.2255. [DOI] [PubMed] [Google Scholar]
  10. Sjögren B., Lundberg I., Lidums V. Aluminium in the blood and urine of industrially exposed workers. Br J Ind Med. 1983 Aug;40(3):301–304. doi: 10.1136/oem.40.3.301. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Slanina P., Frech W., Ekström L. G., Löf L., Slorach S., Cedergren A. Dietary citric acid enhances absorption of aluminum in antacids. Clin Chem. 1986 Mar;32(3):539–541. [PubMed] [Google Scholar]
  12. Yokel R. A., McNamara P. J. Elevated aluminum persists in serum and tissues of rabbits after a six-hour infusion. Toxicol Appl Pharmacol. 1989 Jun 1;99(1):133–138. doi: 10.1016/0041-008x(89)90118-x. [DOI] [PubMed] [Google Scholar]

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