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. 1993 Jun;50(6):549–560. doi: 10.1136/oem.50.6.549

Further follow up of mortality in a United Kingdom oil refinery cohort.

L Rushton 1
PMCID: PMC1035483  PMID: 8329321

Abstract

The results of an extension of follow up (1976 to 1989) of a cohort of workers employed for at least one year between 1 January 1950 and 31 December 1975 at eight oil refineries in Britain are reported. Over 99% of the workers were successfully traced to determine their vital status at 31 December 1989. The mortality observed was compared with that expected from the death rates of all the male population of England and Wales and Scotland. The mortality from all causes of death for the total study population was lower than that of the comparison population, and reduced mortality was also found for many of the major non-malignant causes of death. Raised mortality patterns were found for diseases of the arteries, in particular aortic aneurysm, and accidental fire and explosion, for the total study population, and across several refineries and other subgroups. Mortality from all neoplasms was lower than expected overall, largely due to a deficit of deaths from malignant neoplasm of the lung. Raised mortality from all neoplasms was found for labourers and in particular for malignant neoplasms of the oesophagus, stomach, and lung, although the mortality was also high for all men in this social class in the national population. Regional variations may have accounted for some of the high mortality. There were other raised mortality patterns in malignant neoplasms of the intestine, rectum, larynx, and prostate but these tended to be isolated and not consistent across refineries and other subgroups. As in the earlier follow up there was raised mortality from melanoma in several job groups.

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Selected References

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  1. Austin H., Delzell E., Cole P. Benzene and leukemia. A review of the literature and a risk assessment. Am J Epidemiol. 1988 Mar;127(3):419–439. doi: 10.1093/oxfordjournals.aje.a114820. [DOI] [PubMed] [Google Scholar]
  2. Austin S. G., Schnatter A. R. A cohort mortality study of petrochemical workers. J Occup Med. 1983 Apr;25(4):304–312. [PubMed] [Google Scholar]
  3. Bertazzi P. A., Pesatori A. C., Zocchetti C., Latocca R. Mortality study of cancer risk among oil refinery workers. Int Arch Occup Environ Health. 1989;61(4):261–270. doi: 10.1007/BF00381424. [DOI] [PubMed] [Google Scholar]
  4. Blot W. J., Brinton L. A., Fraumeni J. F., Jr, Stone B. J. Cancer mortality in U.S. counties with petroleum industries. Science. 1977 Oct 7;198(4312):51–53. doi: 10.1126/science.897679. [DOI] [PubMed] [Google Scholar]
  5. Christie D., Robinson K., Gordon I., Bisby J. A prospective study in the Australian petroleum industry. I. Mortality. Br J Ind Med. 1991 Aug;48(8):507–510. doi: 10.1136/oem.48.8.507. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Darby S. C., O'Hagan J. A., Kendall G. M., Doll R., Fell T. P., Muirhead C. R. Completeness of follow up in a cohort study of mortality using the United Kingdom National Health Service Central Registers and records held by the Department of Social Security. J Epidemiol Community Health. 1991 Mar;45(1):65–70. doi: 10.1136/jech.45.1.65. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Divine B. J., Barron V., Kaplan S. D. Texaco mortality study. I. Mortality among refinery, petrochemical, and research workers. J Occup Med. 1985 Jun;27(6):445–447. [PubMed] [Google Scholar]
  8. Fox A. J., Collier P. F. Low mortality rates in industrial cohort studies due to selection for work and survival in the industry. Br J Prev Soc Med. 1976 Dec;30(4):225–230. doi: 10.1136/jech.30.4.225. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Gradiski D., Vinot J., Zissu D., Limasset J. C., Lafontaine M. The carcinogenic effect of a series of petroleum-derived oils on the skin of mice. Environ Res. 1983 Dec;32(2):258–268. doi: 10.1016/0013-9351(83)90110-x. [DOI] [PubMed] [Google Scholar]
  10. Hanis N. M., Shallenberger L. G., Donaleski D. L., Sales E. A. A retrospective mortality study of workers in three major U.S. refineries and chemical plants. Part 1: Comparisons with U.S. population. J Occup Med. 1985 Apr;27(4):283–292. [PubMed] [Google Scholar]
  11. Hanis N. M., Stavraky K. M., Fowler J. L. Cancer mortality in oil refinery workers. J Occup Med. 1979 Mar;21(3):167–174. [PubMed] [Google Scholar]
  12. Harrington J. M. Health experience of workers in the petroleum manufacturing and distribution industry: a review of the literature. Am J Ind Med. 1987;12(5):475–497. doi: 10.1002/ajim.4700120503. [DOI] [PubMed] [Google Scholar]
  13. Holland J. M., Rahn R. O., Smith L. H., Clark B. R., Chang S. S., Stephens T. J. Skin carcinogenicity of synthetic and natural petroleums. J Occup Med. 1979 Sep;21(9):614–618. [PubMed] [Google Scholar]
  14. Hoover R., Fraumeni J. F., Jr Cancer mortality in U.S. counties with chemical industries. Environ Res. 1975 Apr;9(2):196–207. doi: 10.1016/0013-9351(75)90064-x. [DOI] [PubMed] [Google Scholar]
  15. Jones D. R., Rushton L. Simultaneous inference in epidemiological studies. Int J Epidemiol. 1982 Sep;11(3):276–282. doi: 10.1093/ije/11.3.276. [DOI] [PubMed] [Google Scholar]
  16. Järvholm B., Lavenius B. Mortality and cancer morbidity in workers exposed to cutting fluids. Arch Environ Health. 1987 Nov-Dec;42(6):361–366. doi: 10.1080/00039896.1987.9934360. [DOI] [PubMed] [Google Scholar]
  17. Kaldor J., Harris J. A., Glazer E., Glaser S., Neutra R., Mayberry R., Nelson V., Robinson L., Reed D. Statistical association between cancer incidence and major-cause mortality, and estimated residential exposure to air emissions from petroleum and chemical plants. Environ Health Perspect. 1984 Mar;54:319–332. doi: 10.1289/ehp.8454319. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Kaplan S. D. Update of a mortality study of workers in petroleum refineries. J Occup Med. 1986 Jul;28(7):514–516. doi: 10.1097/00043764-198607000-00012. [DOI] [PubMed] [Google Scholar]
  19. Mehlman M. A. Dangerous properties of petroleum-refining products: carcinogenicity of motor fuels (gasoline). Teratog Carcinog Mutagen. 1990;10(5):399–408. doi: 10.1002/tcm.1770100505. [DOI] [PubMed] [Google Scholar]
  20. Miller B. G., Cowie H. A., Middleton W. G., Seaton A. Epidemiologic studies of Scottish oil shale workers: III. Causes of death. Am J Ind Med. 1986;9(5):433–446. doi: 10.1002/ajim.4700090505. [DOI] [PubMed] [Google Scholar]
  21. Nelson N. A., Van Peenen P. F., Blanchard A. G. Mortality in a recent oil refinery cohort. J Occup Med. 1987 Jul;29(7):610–612. [PubMed] [Google Scholar]
  22. Norell S., Ahlbom A., Olin R., Erwald R., Jacobson G., Lindberg-Navier I., Wiechel K. L. Occupational factors and pancreatic cancer. Br J Ind Med. 1986 Nov;43(11):775–778. doi: 10.1136/oem.43.11.775. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Reeve G. R., Thomas T. L., Kelly V. F., Waxweiler R. J., Itaya S. A proportionate mortality study of an Oil, Chemical and Atomic Workers Local in Texas City, Texas. Ann N Y Acad Sci. 1982;381:54–61. doi: 10.1111/j.1749-6632.1982.tb50367.x. [DOI] [PubMed] [Google Scholar]
  24. Rushton L., Alderson M. R. An epidemiological survey of eight oil refineries in Britain. Br J Ind Med. 1981 Aug;38(3):225–234. doi: 10.1136/oem.38.3.225. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Savitz D. A., Moure R. Cancer risk among oil refinery workers. A review of epidemiologic studies. J Occup Med. 1984 Sep;26(9):662–670. [PubMed] [Google Scholar]
  26. Siemiatycki J., Dewar R., Richardson L. Costs and statistical power associated with five methods of collecting occupation exposure information for population-based case-control studies. Am J Epidemiol. 1989 Dec;130(6):1236–1246. doi: 10.1093/oxfordjournals.aje.a115452. [DOI] [PubMed] [Google Scholar]
  27. Swaen G. M., Meijers J. M. Risk assessment of leukaemia and occupational exposure to benzene. Br J Ind Med. 1989 Dec;46(12):826–830. doi: 10.1136/oem.46.12.826. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Thomas T. L., Waxweiler R. J., Crandall M. S., White D. W., Moure-Eraso R., Fraumeni J. F., Jr Cancer mortality patterns by work category in three Texas oil refineries. Am J Ind Med. 1984;6(1):3–16. doi: 10.1002/ajim.4700060103. [DOI] [PubMed] [Google Scholar]
  29. Thomas T. L., Waxweiler R. J., Crandall M. S., White D. W., Moure-Eraso R., Itaya S., Fraumeni J. F., Jr Brain cancer among OCAW members in three Texas oil refineries. Ann N Y Acad Sci. 1982;381:120–129. doi: 10.1111/j.1749-6632.1982.tb50376.x. [DOI] [PubMed] [Google Scholar]
  30. Thomas T. L., Waxweiler R. J., Moure-Eraso R., Itaya S., Fraumeni J. F., Jr Mortality patterns among workers in three Texas oil refineries. J Occup Med. 1982 Feb;24(2):135–141. [PubMed] [Google Scholar]
  31. Thériault G., Provencher S. Mortality study of oil refinery workers: five-year follow-up. J Occup Med. 1987 Apr;29(4):357–360. [PubMed] [Google Scholar]
  32. Van Peenen P. F., Blanchard A. G., Wolkonsky P. M. Smoking habits of oil refinery employees. Am J Public Health. 1984 Dec;74(12):1408–1409. doi: 10.2105/ajph.74.12.1408. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Waxweiler R. J., Alexander V., Leffingwell S. S., Haring M., Lloyd J. W. Mortality from brain tumor and other causes in a cohort of petrochemical workers. J Natl Cancer Inst. 1983 Jan;70(1):75–81. [PubMed] [Google Scholar]
  34. Wen C. P., Tsai S. P., McClellan W. A., Gibson R. L. Long-term mortality study of oil refinery workers. I. Mortality of hourly and salaried workers. Am J Epidemiol. 1983 Oct;118(4):526–542. doi: 10.1093/oxfordjournals.aje.a113658. [DOI] [PubMed] [Google Scholar]
  35. Wen C. P., Tsai S. P., Weiss N. S., Gibson R. L. Long-term mortality study of oil refinery workers: V. Comparison of workers hired before, during, and after World War II (1940-1945) with a discussion of the impact of study designs on cohort results. Am J Ind Med. 1986;9(2):171–180. doi: 10.1002/ajim.4700090208. [DOI] [PubMed] [Google Scholar]
  36. Wong O., Morgan R. W., Bailey W. J., Swencicki R. E., Claxton K., Kheifets L. An epidemiological study of petroleum refinery employees. Br J Ind Med. 1986 Jan;43(1):6–17. doi: 10.1136/oem.43.1.6. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Wong O., Raabe G. K. Critical review of cancer epidemiology in petroleum industry employees, with a quantitative meta-analysis by cancer site. Am J Ind Med. 1989;15(3):283–310. doi: 10.1002/ajim.4700150305. [DOI] [PubMed] [Google Scholar]

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