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Non-inferiority margins based on varying standard deviations (SDs)
| Standard deviation | Non-inferiority margin on Log10 scale |
|---|---|
| Standardised standard deviation (SD = 1) on the Log10 scale | − 0.35 (Cohen’s d) |
| Assuming an SD of 0.6 on the Log10 scale [20] | − 0.21 (equivalent to a GMR of 0.62) |
| Assuming an SD of 0.2 on the Log10 scale [23] | − 0.07 (equivalent to a GMR of 0.85) |
