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. 2016 Sep 1;99(3):327–334. doi: 10.3184/003685016X14720691270831

From ‘Mad Honey’ to Hypotensive Agents, the Grayanoid Diterpenes

James R Hanson 1,✉
PMCID: PMC10365501  PMID: 28742492

Abstract

The toxicity of Rhododendron species and other members of the Ericaceae which is due to the grayanoid diterpenes, is described. Their structures, biogenesis and biological activity is reviewed.

Keywords: Rhododendron species, Ericaceae, grayanotoxins, honey, poisons, hypotensive agents

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