Abstract
A radiological follow-up of the miners and ex-miners in two Welsh mining valleys whose chest radiographs showed simple pneumoconiosis in 1950/51 has been carried out to study the factors associated with the attack rate of progressive massive fibrosis. The radiographs were read in pairs, and also with the pairs separated, the radiographs being randomized and identifying features concealed. The relative value of these two types of reading is discussed.
An attempt to investigate the importance of exogenous tuberculous infection by comparing the attack rate in the two mining valleys, in one of which great efforts had been made to eradicate tuberculosis, failed. The reasons for the failure are discussed.
No evidence was found of any association between the attack rate of progressive massive fibrosis and age, energy expenditure at work, smoking habits, body type, exogenous tuberculous infection, or endogenous infection as measured by the presence of primary complexes in the first radiographs. The only factor related to the attack rate was the average category of simple pneumoconiosis. The attack rate is zero at category ½ and rises to 30 or more per 100 in eight years for category 3. It is argued from this that the logical way to control the appearance of progressive massive fibrosis is to concentrate on preventing miners reaching category 2 of simple pneumoconiosis. Evidence is also presented that considerable progression of simple pneumoconiosis has been occurring during the past eight years amongst coal-face workers at the collieries in this area.
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- ATTYGALLE D., HARRISON C. V., KING E. J., MOHANTY G. P. Infective pneumoconiosis. I. The influence of dead tubercle bacilli (BCG) on the dust lesions produced by anthracite, coal-mine dust, and kaolin in the lungs of rats and guinea-pigs. Br J Ind Med. 1954 Oct;11(4):245–259. doi: 10.1136/oem.11.4.245. [DOI] [PMC free article] [PubMed] [Google Scholar]
- CHAPMAN P. J., COCHRANE A. L., DAVIES I., RAE S. The prevalence of coalworkers' pneumoconiosis: its measurement and significance. Br J Ind Med. 1956 Oct;13(4):231–250. doi: 10.1136/oem.13.4.231. [DOI] [PMC free article] [PubMed] [Google Scholar]
- COCHRANE A. L., COX J. G., JARMAN T. F. Pulmonary tuberculosis in the Rhondda Fach; an interim report of a survey of a mining community. Br Med J. 1952 Oct 18;2(4789):843–853. doi: 10.1136/bmj.2.4789.843. [DOI] [PMC free article] [PubMed] [Google Scholar]
- COCHRANE A. L., MIALL W. E. Factors influencing the radiological attack rate of progressive massive fibrosis. Br Med J. 1956 May 26;1(4977):1193–1199. doi: 10.1136/bmj.1.4977.1193. [DOI] [PMC free article] [PubMed] [Google Scholar]
- COCHRANE A. L. Tuberculosis and coalworkers' pneumoconiosis. Br J Tuberc Dis Chest. 1954 Oct;48(4):274–285. doi: 10.1016/s0366-0869(54)80127-4. [DOI] [PubMed] [Google Scholar]
- Jarman T. F. Report of Tuberculin Survey in the Rhondda Fach. Br Med J. 1953 Apr 4;1(4813):754–759. doi: 10.1136/bmj.1.4813.754. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KING E. J., HARRISON C. V., MOHANTY G. P., MITCHISON D. A. Experimental infective pneumoconiosis. Arh Hig Rada. 1953;4(3):289–300. [PubMed] [Google Scholar]
- KING E. J., YOGANATHAN M., HARRISON C. V., MITCHISON D. A. Experimental infective pneumoconiosis. V. Massive fibrosis of the lungs produced by coal-mine dust and Mycobacterium tuberculosis var. muris (Vole bacillus). AMA Arch Ind Health. 1957 Nov;16(5):380–392. [PubMed] [Google Scholar]
- RIVERS D., WISE M. E., KING E. J., NAGELSCHMIDT G. Dust content, radiology, and pathology in simple pneumoconiosis of coalworkers. Br J Ind Med. 1960 Apr;17:87–108. [PMC free article] [PubMed] [Google Scholar]
- VIGLIANI E. C., PERNIS B. Immunological factors in the pathogenesis of the hyaline tissue of silicosis. Br J Ind Med. 1958 Jan;15(1):8–14. doi: 10.1136/oem.15.1.8. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WATSON A. J., BLACK J., DOIG A. T., NAGELSCHMIDT G. Pneumoconiosis in carbon electrode makers. Br J Ind Med. 1959 Oct;16:274–285. doi: 10.1136/oem.16.4.274. [DOI] [PMC free article] [PubMed] [Google Scholar]
- ZAIDI S. H., HARRISON C. V., KING E. J., MITCHISON D. A. Experimental infective pneumoconiosis. IV. Massive pulmonary fibrosis produced by coal-mine dust and isoniazid-resistant tubercle bacilli of low virulence. Br J Exp Pathol. 1955 Dec;36(6):553–559. [PMC free article] [PubMed] [Google Scholar]