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. 2023 Jul 5;15(7):1893. doi: 10.3390/pharmaceutics15071893

Table 3.

Amoebolytic substances produced by Bacillus licheniformis.

Substance(s) Specific/Unspecific Name Producing Strain Molecular Mass Activity Assay Reference
Peptide A12-A и A12-B Bacillus licheniformis A12 1.43–1.6 kDa N. fowlen S-3 (=ATCC 30809)
N. fowlen HB-1 (=ATCC 30174)
N. lovaniensis Aq/9/1/45D
N. gruberi CCAP 1516/le
B. megaterium
Cotynebactenum glutamicum CECT 78
Sarcina sp.
B. megaterium
Cotynebactenum glutamicum CECT 78
Sarcina sp.
[107]
Amoebicins M4—a, b, c Bacillus licheniformis M-4 3–3.2 kDa Acanthamoeba sp. Gr-1
Naegleria fowleri S-3 (=ATCC 30809)
N. fowleri HB-1 (=ATCC 30174)
Naegleria lovaniensis Aq/9/1/45D
Naegleria gruberi CCAP 1516/le
[98]
Amoebicins d13-A, d13-B and
d13-C
B. licheniformis strain D-13 1.87 kDa Acanthamoeba sp. strain Gr-1
Naegleria lovaniensis Aq/9/1/45D
Naegleria gruberi CCAP 1516/le
N. fowleri S-3 (=ATCC 30809)
N. fowleri HB-1 (=ATCC 30174)
Alcaligenes facecalis
B. licheniformis M-4, A12
Bacillus megaterium
Corynebacterium glutamicum CECT 78
Enterococcus faecalis S-13, S-14, S-48, S-86
Micrococcus luteus
Mycobacterium phlei
Pseudomonas reptilovora N5
[108]