Table 6.
Antimycobacterial substances produced by Bacillus licheniformis.
| Substance Name | Molecular Mass | Sensitivity to Enzymes | Sensitivity to Temperature | Reference |
|---|---|---|---|---|
| Bacitracin/Ayfivin | 1.42 kDa | ND | Resistant to temperature under 60 °C. | [113,130] |
| Proticin | 0.56 kDa | ND | ND | [38] |
| Peptide A12-C | 0.77 kDa | Resistant to trypsin, pronase and proteinase K, carboxypeptidase A, alkaline phosphatase, lipase, lysozyme, β-glucosidase and β-glucuronidase | resistant to heat (100 °C for 30 min at pH 7.0) | [46] |
| Licheniformins | 3.8–4.8 kDa | ND | ND | [37] |
| Amoebicins d13-A, d13-B, and d13-C | 1.87 kDa | Resistant to trypsin, pronase, proteinase, lipase and β-glucuronidase | retained 100% of the activity after being heated at 100 °C for 30 min and also after being stored at −20 °C for 6 months | [108] |
| Lichenicidin | 3 kDa and 3.25 kDa | No loss of antimicrobial activity after treatment with trypsin and chymotrypsin, inactivation by proteinase K and pronase E | supernatant was inactivated within two hours by 80 °C and within 30 min by boiling | [50,52] |
ND—no data.