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. 2023 Jul 20;28(14):5549. doi: 10.3390/molecules28145549

Table 1.

Biological activities of mono-aromatic steroids (427).

No. Dominated Biological Activity (Pa) * Additional Predicted Activities (Pa) *
4 Ovulation inhibitor (0.942)
Cardiovascular analeptic (0.924)
Apoptosis agonist (0.750)
Anti-hypercholesterolemic (0.871)
Lipid metabolism regulator (0.788)
Prostate disorders treatment (0.737)
5 Anti-hypercholesterolemic (0.894)
Ovulation inhibitor (0.889)
Anesthetic general (0.868)
Respiratory analeptic (0.851)
Acute neurologic disorders treatment (0.793)
Prostate disorders treatment (0.729)
6 Anesthetic general (0.845)
Ovulation inhibitor (0.832)
Acute neurologic disorders treatment (0.822)
Neuroprotector (0.815)
7 Anti-hypercholesterolemic (0.856)
Ovulation inhibitor (0.847)
Cardiovascular analeptic (0.842)
Lipid metabolism regulator (0.788)
Apoptosis agonist (0.750)
Prostate disorders treatment (0.725)
8 Anti-hypercholesterolemic (0.885)
Apoptosis agonist (0.801)
Hepatic disorders treatment (0.739)
Ovulation inhibitor (0.726)
9 Acute neurologic disorders treatment (0.871)
Respiratory analeptic (0.843)
Vasoprotector (0.811)
Neuroprotector (0.785)
Anesthetic general (0.753)
Ovulation inhibitor (0.740)
10 Cardiovascular analeptic (0.882)
Ovulation inhibitor (0.860)
Respiratory analeptic (0.846)
Acute neurologic disorders treatment (0.844)
11 Respiratory analeptic (0.879)
Ovulation inhibitor (0.765)
Neuroprotector (0.762)
Cardiovascular analeptic (0.692)
12 Acute neurologic disorders treatment (0.849)
Vasoprotector (0.795)
Anti-inflammatory (0.788)
Ovulation inhibitor (0.778)
13 Psychotropic (0.815)
Ovulation inhibitor (0.586)
Attention deficit/hyperactivity disorder
treatment (0.744)
14 Postmenopausal disorders treatment (0.945) Anti-inflammatory (0.669)
15 Lipid metabolism regulator (0.913)
Cytostatic (0.891)
Anti-neoplastic (0.876)
Hepatoprotectant (0.845)
Immunosuppressant (0.792)
Apoptosis agonist (0.784)
16 Chemopreventive (0.919)
Proliferative diseases treatment (0.914)
Anti-neoplastic (0.837)
Vasoprotector (0.824)
17 Apoptosis agonist (0.893)
Anti-neoplastic (0.827)
Anti-inflammatory (0.873)
Hypolipemic (0.854)
18 Apoptosis agonist (0.883)
Anti-neoplastic (0.826)
Hypolipemic (0.863)
Anti-inflammatory (0.855)
19 Anti-neoplastic (0.879)
Apoptosis agonist (0.775)
Immunosuppressant (0.744)
Anti-inflammatory (0.715)
20 Anti-neoplastic (0.782) Genital warts treatment (0.736)
21 Apoptosis agonist (0.896)
Anti-neoplastic (0.843)
Hypolipemic (0.850)
Anti-inflammatory (0.814)
22 Chemopreventive (0.887)
Anti-neoplastic (0.794)
Anti-inflammatory (0.819)
Proliferative diseases treatment (0.784)
23 Anti-neoplastic (0.909)
Apoptosis agonist (0.790)
Anti-inflammatory (0.822)
Immunosuppressant (0.727)
24 Anti-neoplastic (0.888)
Apoptosis agonist (0.847)
Anti-inflammatory (0.830)
Immunosuppressant (0.739)
25 Anti-neoplastic (0.802)
Apoptosis agonist (0.789)
Anti-inflammatory (0.786)
Prostate disorders treatment (0.685)
26 Acute neurologic disorders treatment (0.867)
Anti-neoplastic (0.812)
Diuretic (0.813)
Male reproductive dysfunction treatment (0.759)
27 Anti-hypercholesterolemic (0.959) Anti-neoplastic (0.832)

* Only activities with Pa > 0.7 are shown. The main biological activity has a value where Pa is more than 0.7.